Synthesis of biologically active molecules through multicomponent reactions
Focusing on the literature progress since 2002, the present review explores the highly
significant role that multicomponent reactions (MCRs) have played as a very important tool …
significant role that multicomponent reactions (MCRs) have played as a very important tool …
Thiazolidin-2, 4-dione scaffold: an insight into recent advances as antimicrobial, antioxidant, and hypoglycemic agents
Heterocyclic compounds containing nitrogen and sulfur, especially those in the thiazole
family, have generated special interest in terms of their synthetic chemistry, which is …
family, have generated special interest in terms of their synthetic chemistry, which is …
Design, synthesis, DFT, docking studies and ADME prediction of some new coumarinyl linked pyrazolylthiazoles: Potential standalone or adjuvant antimicrobial …
The control of antimicrobial resistance (AMR) seems to have come to a dead end. The major
consequences of the use and abuse of antibacterial drugs are the development of resistant …
consequences of the use and abuse of antibacterial drugs are the development of resistant …
[HTML][HTML] One-pot three-component synthesis of novel phenyl-pyrano-thiazol-2-one derivatives and their anti-diabetic activity studies
An easy and rapid synthetic approach for the synthesis of phenyl-pyrano-thiazol-2-one
derivatives using base catalysed one-pot three-component reaction between substituted …
derivatives using base catalysed one-pot three-component reaction between substituted …
Thiazolidine‐4‐one clubbed pyrazoles hybrids: Potent α‐amylase and α‐glucosidase inhibitors with NLO properties
Molecular hybrids based on thiazolidin‐4‐one and pyrazolyl pharmacophore (THZP) as new
antidiabetic agents were synthesized. Two sets of signals came into view in 1H NMR of …
antidiabetic agents were synthesized. Two sets of signals came into view in 1H NMR of …
Chemistry and applications of functionalized 2, 4‐thiazolidinediones
AM Ibrahim, ME Shoman… - European Journal of …, 2023 - Wiley Online Library
Thiazolidinedione (TZD) is one of the privileged heterocyclic rings and has shown many
biological applications in medicinal chemistry and drug discovery. This review covers the …
biological applications in medicinal chemistry and drug discovery. This review covers the …
An environmental friendly approach for the catalyst-free synthesis of highly substituted pyrazoles promoted by ultrasonic radiation
F Nemati, SH Nikkhah, A Elhampour - Chinese Chemical Letters, 2015 - Elsevier
A cost-effective, highly useful and eco-friendly procedure for the one-pot synthesis of highly
substituted pyrazole derivatives has been developed via the reaction of various aldehydes …
substituted pyrazole derivatives has been developed via the reaction of various aldehydes …
Synthesis and biological evaluation of some functionalized 1H-1,2,3-triazole tethered pyrazolo[3,4-b]pyridin-6(7H)-ones as antimicrobial and apoptosis inducing …
A series of novel molecular hybrids containing pyrazole, pyridinone and 1, 2, 3-triazoles
have been synthesized by one-pot four-component reaction of Meldrum's acid, substituted …
have been synthesized by one-pot four-component reaction of Meldrum's acid, substituted …
Synthesis, antimicrobial evaluation, and molecular docking studies of novel chromone based 1, 2, 3-triazoles
In Search of novel antimicrobial agents with improved potency, we designed and
synthesized a series of 3-((1-benzyl-1 H-1, 2, 3-triazol-4-yl) methoxy)-2-(4-fluorophenyl)-4 H …
synthesized a series of 3-((1-benzyl-1 H-1, 2, 3-triazol-4-yl) methoxy)-2-(4-fluorophenyl)-4 H …
Microwave-assisted green synthesis of new imidazo[2,1-b]thiazole derivatives and their antimicrobial, antimalarial, and antitubercular activities
RH Vekariya, KD Patel, MK Vekariya… - Research on Chemical …, 2017 - Springer
We have synthesized some imidazo [2, 1-b] thiazole derivatives by reaction of 1-(2-amino-4-
methylthiazol-5-yl) ethanone or ethyl 2-amino-4-methylthiazole-5-carboxylate with α-bromo …
methylthiazol-5-yl) ethanone or ethyl 2-amino-4-methylthiazole-5-carboxylate with α-bromo …