Conspectus So far, over 150 natural products and pharmaceuticals containing an allene
moiety have been identified. During the last two decades, allenes have also been …

Allene moieties with axial chirality are featured in many natural products with biological
activities. They also serve as unique building blocks in organic synthesis and as chiral …

Oxidation from alcohols to carboxylic acids, a class of essential chemicals in daily life,
academic laboratories, and industry, is a fundamental reaction, usually using at least a …

The general enantioselective catalytic synthesis of axially chiral 1, 3-disubstituted allenes
from readily available racemic propargylic alcohol derivatives remains a long-standing …

A highly enantioselective synthesis of trisubstituted allenes has been achieved through Cu
(I)-catalyzed cross-coupling of aryldiazoalkanes and terminal alkynes with chiral …

The general enantioselective synthesis of axially chiral disubstituted allenes from prochiral
starting materials remains a long-standing challenge in organic synthesis. Here, we report …

Allenes are useful functional groups in synthesis as a result of their inherent chemical
properties and established reactivity patterns. One property of chemical bonding renders 1 …

Metal-catalyzed enantioselective construction of the loosening axial allene chirality
spreading over three carbon atoms using a chiral ligand is still a significant challenge. In the …

The use of alkyl amines and ethers as traceless hydride donors in [1, 5]-hydride transfer
cascade reactions represents a promising strategy that greatly enriches redox-neutral …

Herein we report the first example of a Pd-catalyzed highly selective three-component
reaction of alkynyl-1, 4-diol dicarbonates, organoboronic acids, and malonate anions for the …