Epidemiology and risk of cardiovascular disease in populations with chronic kidney disease

K Matsushita, SH Ballew, AYM Wang… - Nature Reviews …, 2022 - nature.com
Chronic kidney disease (CKD) is defined by a low glomerular filtration rate or high
albuminuria, and affects 15–20% of adults globally. CKD increases the risk of various …

Cardiovascular disease in chronic kidney disease: pathophysiological insights and therapeutic options

J Jankowski, J Floege, D Fliser, M Böhm, N Marx - Circulation, 2021 - Am Heart Assoc
Patients with chronic kidney disease (CKD) exhibit an elevated cardiovascular risk
manifesting as coronary artery disease, heart failure, arrhythmias, and sudden cardiac …

Signaling pathways of chronic kidney diseases, implications for therapeutics

Q Yuan, B Tang, C Zhang - Signal transduction and targeted therapy, 2022 - nature.com
Chronic kidney disease (CKD) is a chronic renal dysfunction syndrome that is characterized
by nephron loss, inflammation, myofibroblasts activation, and extracellular matrix (ECM) …

Targeting innate immunity-driven inflammation in CKD and cardiovascular disease

T Speer, S Dimmeler, SJ Schunk, D Fliser… - Nature Reviews …, 2022 - nature.com
Mortality among patients with chronic kidney disease (CKD) is largely a consequence of
cardiovascular disease (CVD) and is a particular concern given the increasing prevalence of …

Lipoproteins and fatty acids in chronic kidney disease: molecular and metabolic alterations

H Noels, M Lehrke, R Vanholder… - Nature Reviews …, 2021 - nature.com
Chronic kidney disease (CKD) induces modifications in lipid and lipoprotein metabolism and
homeostasis. These modifications can promote, modulate and/or accelerate CKD and …

Immune dysfunction in uremia 2020

G Cohen - Toxins, 2020 - mdpi.com
Cardiovascular disease and infections are major causes for the high incidence of morbidity
and mortality of patients with chronic kidney disease. Both complications are directly or …

Hemodialysis‐induced cardiovascular disease

S Ahmadmehrabi, WHW Tang - Seminars in Dialysis, 2018 - Wiley Online Library
More than half of all deaths among end stage renal disease (ESRD) patients are due to
cardiovascular disease (CVD). Cardiovascular changes secondary to renal dysfunction …

Advances in HDL: much more than lipid transporters

S Ben-Aicha, L Badimon, G Vilahur - International Journal of Molecular …, 2020 - mdpi.com
High Density Lipoprotein (HDL) particles, beyond serving as lipid transporters and playing a
key role in reverse cholesterol transport, carry a highly variable number of proteins, micro …

High density lipoproteins: metabolism, function, and therapeutic potential

A Jomard, E Osto - Frontiers in cardiovascular medicine, 2020 - frontiersin.org
High Density Lipoproteins (HDLs) have long been considered as “good cholesterol,”
beneficial to the whole body and, in particular, to cardio-vascular health. However, HDLs are …

Precise metabolomics reveals a diversity of aging‐associated metabolic features

H Tian, Z Ni, SM Lam, W Jiang, F Li, J Du… - Small …, 2022 - Wiley Online Library
Mass spectrometry‐based metabolomics has emerged as a powerful technique for
biomedical research, although technical issues with its analytical precision and structural …