The bioelectric code: An ancient computational medium for dynamic control of growth and form

M Levin, CJ Martyniuk - Biosystems, 2018 - Elsevier
What determines large-scale anatomy? DNA does not directly specify geometrical
arrangements of tissues and organs, and a process of encoding and decoding for …

[HTML][HTML] Pregenerative medicine: developmental paradigms in the biology of cardiovascular regeneration

BA Yi, O Wernet, KR Chien - The Journal of clinical …, 2010 - Am Soc Clin Investig
The ability to create new functional cardiomyocytes is the holy grail of cardiac regenerative
medicine. From studies using model organisms, new insights into the fundamental pathways …

[HTML][HTML] CRISPR-mediated genomic deletion of Sox2 in the axolotl shows a requirement in spinal cord neural stem cell amplification during tail regeneration

JF Fei, M Schuez, A Tazaki, Y Taniguchi, K Roensch… - Stem cell reports, 2014 - cell.com
The salamander is the only tetrapod that functionally regenerates all cell types of the limb
and spinal cord (SC) and thus represents an important regeneration model, but the lack of …

Transcriptomic, proteomic, and metabolomic landscape of positional memory in the caudal fin of zebrafish

JS Rabinowitz, AM Robitaille, Y Wang… - Proceedings of the …, 2017 - National Acad Sciences
Regeneration requires cells to regulate proliferation and patterning according to their spatial
position. Positional memory is a property that enables regenerating cells to recall spatial …

[HTML][HTML] Regeneration and transdetermination: the role of wingless and its regulation

M Schubiger, A Sustar, G Schubiger - Developmental biology, 2010 - Elsevier
Imaginal discs of Drosophila have the remarkable ability to regenerate. After fragmentation
wound healing occurs, ectopic wg is induced and a blastema is formed. In some, but not all …

[HTML][HTML] Keeping at arm's length during regeneration

VA Tornini, KD Poss - Developmental cell, 2014 - cell.com
Regeneration of a lost appendage in adult amphibians and fish is a remarkable feat of
developmental patterning. Although the limb or fin may be years removed from its initial …

Regeneration of pancreatic insulin-producing cells by in situ adaptive cell conversion

S Chera, PL Herrera - Current opinion in genetics & development, 2016 - Elsevier
The impaired ability to produce or respond to insulin, a hormone synthetized by the
pancreatic β-cells, leads to diabetes. There is an excruciating need of finding new …

[HTML][HTML] On a model of pattern regeneration based on cell memory

N Bessonov, M Levin, N Morozova, N Reinberg… - PloS one, 2015 - journals.plos.org
We present here a new model of the cellular dynamics that enable regeneration of complex
biological morphologies. Biological cell structures are considered as an ensemble of …

[HTML][HTML] Diffusion tensor tractography reveals muscle reconnection during axolotl limb regeneration

CH Wu, YJ Chen, MH Wang, LL Chiou, WYI Tseng… - Plos one, 2017 - journals.plos.org
Axolotls have amazing ability to regenerate their lost limbs. Our previous works showed that
after amputation the remnant muscle ends remained at their original location whilst sending …

Identification and characterization of POU class V family genes in Japanese red bellied newt, Cynops pyrrhogaster

S Hasegawa, I Nakao, Y Ootani, A Ogawa, M Takano… - Zygote, 2019 - cambridge.org
Mammalian Pou5f1 encodes the POU family class V (POU-V) transcription factor which is
essential for the pluripotency of embryonic cells and germ cells. In vertebrates, various POU …