MiT family translocation renal cell carcinoma: from the early descriptions to the current knowledge

A Caliò, D Segala, E Munari, M Brunelli, G Martignoni - Cancers, 2019 - mdpi.com
The new category of MiT family translocation renal cell carcinoma has been included into
the World Health Organization (WHO) classification in 2016. The MiT family translocation …

[HTML][HTML] RBM10: structure, functions, and associated diseases

A Inoue - Gene, 2021 - Elsevier
RBM10 is a nuclear RNA-binding protein (RBP) that regulates the alternative splicing of
primary transcripts. Recently, research on RBM10 has become increasingly active owing to …

Multiple Omics Analysis of the Role of RBM10 Gene Instability in Immune Regulation and Drug Sensitivity in Patients with Lung Adenocarcinoma (LUAD)

L Wu, Q Liu, X Ruan, X Luan, Y Zhong, J Liu, J Yan… - Biomedicines, 2023 - mdpi.com
Objective: The RNA-binding protein RBM10 can regulate apoptosis during the proliferation
and migration of pancreatic cancer, endometrial cancer, and osteosarcoma cells; however …

Start of a new era: Management of non-clear cell renal cell carcinoma in 2022

BL Maughan - Current Oncology Reports, 2022 - Springer
Abstract Purpose of Review Historically, kidney cancer was diagnosed as either clear cell
renal carcinoma (ccRCC) or non-clear cell renal carcinoma (nccRCC). With further research …

Chameleon TFE3-translocation RCC and how gene partners can change morphology: accurate diagnosis using contemporary modalities

MS Tretiakova - Advances in Anatomic Pathology, 2022 - journals.lww.com
Translocation renal cell carcinoma (tRCC) with TFE3 gene rearrangements has been born
as a distinct entity 20 years ago. These relatively rare tumors were notable among other …

Immunohistochemistry for the diagnosis of renal epithelial neoplasms

M Akgul, SR Williamson - Seminars in Diagnostic Pathology, 2022 - Elsevier
Despite the increasing number of newly identified renal neoplasms, the diagnosis of renal
cell carcinoma (RCC) can usually be reached with careful histologic examination and a …

Advanced non-clear cell renal cell carcinoma treatments and survival: a real-world single-centre experience

D Bimbatti, F Pierantoni, E Lai, M Ballestrin, N Cavasin… - Cancers, 2023 - mdpi.com
Simple Summary Non-clear cell renal cell carcinoma (nccRCC) represents about the 20% of
all RCCs but recommendations on treatment lacks evidence since the clinical trials include …

[HTML][HTML] Diagnostic utility of one-stop fusion gene panel to detect TFE3/TFEB gene rearrangement and amplification in renal cell carcinomas

S Harada, A Caliò, KM Janowski, D Morlote… - Modern Pathology, 2021 - Elsevier
MiT family translocation renal cell carcinoma (MiT-RCC) harbors translocations involving the
TFE3 or TFEB genes. RCC with TFEB amplification is also identified and is associated with a …

Molecular genetics of renal cell tumors: A practical diagnostic approach

R Alaghehbandan, D Perez Montiel, AS Luis, O Hes - Cancers, 2019 - mdpi.com
Renal epithelial cell tumors are composed of a heterogeneous group of tumors with variable
morphologic, immunohistochemical, and molecular features. A “histo-molecular” approach is …

Clinicopathological findings on 28 cases with XP11. 2 renal cell carcinoma

L Kuthi, Á Somorácz, T Micsik, A Jenei, A Hajdu… - Pathology & Oncology …, 2020 - Springer
Xp11. 2 translocation carcinoma is a distinct subtype of renal cell carcinoma characterized
by translocations involving the TFE3 gene. Our study included the morphological …