This review presents the latest innovations and trends in the field of surface functionalization
of various nanomaterials. The most recent protocols of smart materials fabrication as well as …

Biomedical implants have been widely used in various orthopedic treatments, including total
hip arthroplasty, joint arthrodesis, fracture fixation, non-union, dental repair, etc. The modern …

Titanium implants have been widely used in bone tissue engineering for decades. However,
orthopedic implant-associated infections increase the risk of implant failure and even lead to …

The reconstruction of large cranial bone defects by bioactive materials without exogenous
cells or growth factors remains a substantial clinical challenge. Here, synthetic fibrous …

Osseointegration is a sophisticated bone and implant healing process comprising of initial
hematoma formation, immediate osteoimmunomodulation, angiogenesis, and osteogenesis …

Recently, zinc and its alloys have been proposed as promising candidates for
biodegradable metals (BMs), owning to their preferable corrosion behavior and acceptable …

Osseointegration of implants is a complex physiological process that requires temporal and
spatial regulation of immune responses, angiogenesis, and osteogenesis. To achieve …

Background The regeneration of periodontal bone defect remains a vital clinical challenge.
To date, numerous biomaterials have been applied in this field. However, the immune …

Diabetes mellitus is a chronic metabolic disease with a proinflammatory microenvironment,
causing poor vascularization and bone regeneration. Due to the lack of effective therapy and …

The cytokines released by immune cells are considered important factors to induce bone
tissue regeneration. However, the pathway of those bone‐targeting macrophage cytokines …