Executive (dys) function after traumatic brain injury: special considerations for behavioral pharmacology

JE Ozga, JM Povroznik… - Behavioural …, 2018 - journals.lww.com
Executive function is an umbrella term that includes cognitive processes such as decision-
making, impulse control, attention, behavioral flexibility, and working memory. Each of these …

Catecholamines and cognition after traumatic brain injury

PO Jenkins, MA Mehta, DJ Sharp - Brain, 2016 - academic.oup.com
Cognitive problems are one of the main causes of ongoing disability after traumatic brain
injury. The heterogeneity of the injuries sustained and the variability of the resulting …

Alcohol abuse after traumatic brain injury: Experimental and clinical evidence

ZM Weil, JD Corrigan, K Karelina - Neuroscience & Biobehavioral Reviews, 2016 - Elsevier
Brain injury survivors, particularly those injured early in life are very likely to abuse drugs
and alcohol later in life. Alcohol abuse following traumatic brain injury (TBI) is associated …

Multi-dimensional mapping of brain-derived extracellular vesicle microRNA biomarker for traumatic brain injury diagnostics

J Ko, M Hemphill, Z Yang, K Beard, E Sewell… - Journal of …, 2020 - liebertpub.com
The diagnosis and prognosis of traumatic brain injury (TBI) is complicated by variability in
the type and severity of injuries and the multiple endophenotypes that describe each …

Senescence-associated-β-galactosidase staining following traumatic brain injury in the mouse cerebrum

T Tominaga, R Shimada, Y Okada, T Kawamata… - PLoS …, 2019 - journals.plos.org
Primary and secondary traumatic brain injury (TBI) can cause tissue damage by inducing
cell death pathways including apoptosis, necroptosis, and autophagy. However, similar …

Impact of traumatic brain injury on dopaminergic transmission

YH Chen, EYK Huang, TT Kuo, J Miller… - Cell …, 2017 - journals.sagepub.com
Brain trauma is often associated with severe morbidity and is a major public health concern.
Even when injury is mild and no obvious anatomic disruption is seen, many individuals …

Dopaminergic abnormalities following traumatic brain injury

PO Jenkins, S De Simoni, NJ Bourke, J Fleminger… - Brain, 2018 - academic.oup.com
Traumatic brain injury can reduce striatal dopamine levels. The cause of this is uncertain,
but is likely to be related to damage to the nigrostriatal system. We investigated the pattern of …

Pioglitazone attenuates neuroinflammation and promotes dopaminergic neuronal survival in the nigrostriatal system of rats after diffuse brain injury

M Liu, AD Bachstetter, WA Cass, J Lifshitz… - Journal of …, 2017 - liebertpub.com
Increasing evidence suggests that traumatic brain injury (TBI) may raise the risk of
developing late-onset Parkinson's disease (PD). Recently, the peroxisome proliferation …

Dysregulation of the dopaminergic system secondary to traumatic brain injury: implications for mood and anxiety disorders

A Mata-Bermudez, R Trejo-Chávez… - Frontiers in …, 2024 - frontiersin.org
Traumatic brain injury (TBI) represents a public health issue with a high mortality rate and
severe neurological and psychiatric consequences. Mood and anxiety disorders are some of …

Adolescent traumatic brain injury induces chronic mesolimbic neuroinflammation with concurrent enhancement in the rewarding effects of cocaine in mice during …

SF Merkel, R Razmpour, EM Lutton… - Journal of …, 2017 - liebertpub.com
Clinical psychiatric disorders of depression, anxiety, and substance abuse are most
prevalent after traumatic brain injury (TBI). Pre-clinical research has focused on depression …