Amplification-free CRISPR/Cas detection technology: challenges, strategies, and perspectives

H Li, Y Xie, F Chen, H Bai, L Xiu, X Zhou… - Chemical Society …, 2023 - pubs.rsc.org
Rapid and accurate molecular diagnosis is a prerequisite for precision medicine, food
safety, and environmental monitoring. The clustered regularly interspaced short palindromic …

Ten years of lateral flow immunoassay technique applications: Trends, challenges and future perspectives

F Di Nardo, M Chiarello, S Cavalera, C Baggiani… - Sensors, 2021 - mdpi.com
The Lateral Flow Immunoassay (LFIA) is by far one of the most successful analytical
platforms to perform the on-site detection of target substances. LFIA can be considered as a …

Co‐based Nanozymatic Profiling: Advances Spanning Chemistry, Biomedical, and Environmental Sciences

J Li, X Cai, P Jiang, H Wang, S Zhang, T Sun… - Advanced …, 2024 - Wiley Online Library
Nanozymes, next‐generation enzyme‐mimicking nanomaterials, have entered an era of
rational design; among them, Co‐based nanozymes have emerged as captivating players …

Enhancing CRISPR-Cas-mediated detection of nucleic acid and non-nucleic acid targets using enzyme-labeled reporters

D Samanta, SB Ebrahimi, N Ramani… - Journal of the American …, 2022 - ACS Publications
We introduce a new method to generate an amplified signal in CRISPR-Cas-based
detection. Target recognition activates a CRISPR-Cas complex, leading to catalytic cleavage …

Pomegranate-bionic encapsulating horseradish peroxidase using dopamine flexible scaffold-coated multishell porous ZIF-8 to enhance immunochromatographic …

M Song, J Xing, H Cai, X Gao, C Li, C Liu, X Li, X Fu… - AcS Nano, 2023 - ACS Publications
Nanoparticle-natural enzyme complexes are receiving increasing attention as the promising
signal reporters for colorimetric lateral flow immunoassay (LFIA). Nonetheless, it remains a …

The nanozyme revolution: Enhancing the performance of medical biosensing platforms

A Shamsabadi, T Haghighi, S Carvalho… - Advanced …, 2024 - Wiley Online Library
Nanozymes represent a class of nanosized materials that exhibit innate catalytic properties
similar to biological enzymes. The unique features of these materials have positioned them …

Evaluation of the multidimensional enhanced lateral flow immunoassay in point-of-care nanosensors

S Liu, Y Liao, R Shu, J Sun, D Zhang, W Zhang… - ACS …, 2024 - ACS Publications
Point-of-care (POC) nanosensors with high screening efficiency show promise for user-
friendly manipulation in the ever-increasing on-site analysis demand for illness diagnosis …

Gold/platinum bimetallic nanomaterials for immunoassay and immunosensing

M Zhang, X Guo - Coordination Chemistry Reviews, 2022 - Elsevier
Bimetallic nanoparticles, considered as great promising nanomaterials nowadays, were
significantly superior to monometallic nanoparticles as a result of their improved nanozyme …

Recent progress in rapid determination of mycotoxins based on emerging biorecognition molecules: A review

Y Wang, C Zhang, J Wang, D Knopp - Toxins, 2022 - mdpi.com
Mycotoxins are secondary metabolites produced by fungal species, which pose significant
risk to humans and livestock. The mycotoxins which are produced from Aspergillus …

An artificial miniaturized peroxidase for signal amplification in lateral flow immunoassays

E Renzi, A Piper, F Nastri, A Merkoçi, A Lombardi - Small, 2023 - Wiley Online Library
Signal amplification strategies are widely used for improving the sensitivity of lateral flow
immunoassays (LFiAs). Herein, the artificial miniaturized peroxidase Fe (III)‐MimochromeVI …