Digestive tract cancers, including esophageal, gastric, and colorectal cancers, are the major
cause of death among cancer patients worldwide due to the heterogeneity of cancer cells …

Metabolic reprogramming is a hallmark of malignancy. Testes-specific protease 50 (TSP50),
a newly identified oncogene, has been shown to play an important role in tumorigenesis …

Background TSP50 (testes-specific protease 50) has been reported to be a candidate
oncogene and is overexpressed in various cancers. Our previous study demonstrated that …

Objective. To investigate the expression of transducin‐(β‐) like 1 X‐linked receptor 1
(TBL1XR1) in human gastric cancer (GC) and its correlation with prognostic and biologic …

The aim of the present study was to investigate the expression of transducer of ErbB2. 1
(TOB1) in gastric carcinoma and to clarify the association between TOB1 expression and the …

Multiple morphological abnormalities of the sperm flagella (MMAF) are a major cause of
asthenoteratozoospermia. We have identified protease serine 50 (PRSS50) as having a …

The integrity of the intestinal mucosal barrier is crucial for protecting the intestinal epithelium
against invasion by commensal bacteria and pathogens, thereby combating colitis. The …

Previous studies have shown that testes-specific protease 50 (TSP50), a pro-oncogene
overexpressed in many types of tumors, could promote cell proliferation, invasion …

Testes-specific protease 50 (TSP50) is abnormally overexpressed in many kinds of cancers
and promotes cell proliferation and migration. However, whether TSP50 can influence the …

Serine protease 50 (PRSS50/TSP50) is highly expressed in spermatocytes. Our study
investigated its role in testicular development and spermatogenesis. Initially, PRSS50 …