Nanomaterials for in vivo imaging

BR Smith, SS Gambhir - Chemical reviews, 2017 - ACS Publications
In vivo imaging, which enables us to peer deeply within living subjects, is producing
tremendous opportunities both for clinical diagnostics and as a research tool. Contrast …

[HTML][HTML] Assessing sample and miRNA profile quality in serum and plasma or other biofluids

T Blondal, SJ Nielsen, A Baker, D Andreasen… - Methods, 2013 - Elsevier
MicroRNAs (miRNAs) constitute a class of small cellular RNAs (typically 21–23nt) that
function as post-transcriptional regulators of gene expression. Current estimates indicate …

Absolute quantification by droplet digital PCR versus analog real-time PCR

CM Hindson, JR Chevillet, HA Briggs, EN Gallichotte… - Nature …, 2013 - nature.com
Nanoliter-sized droplet technology paired with digital PCR (ddPCR) holds promise for highly
precise, absolute nucleic acid quantification. Our comparison of microRNA quantification by …

Characterization of human plasma-derived exosomal RNAs by deep sequencing

X Huang, T Yuan, M Tschannen, Z Sun, H Jacob, M Du… - BMC genomics, 2013 - Springer
Background Exosomes, endosome-derived membrane microvesicles, contain specific RNA
transcripts that are thought to be involved in cell-cell communication. These RNA transcripts …

Circulating miRNAs: roles in cancer diagnosis, prognosis and therapy

G Cheng - Advanced drug delivery reviews, 2015 - Elsevier
MicroRNAs (miRNAs) belong to a class of small non-coding RNAs that regulate numerous
biological processes by targeting a broad set of messenger RNAs. Recently, miRNAs have …

Haemolysis during sample preparation alters microRNA content of plasma

MB Kirschner, SC Kao, JJ Edelman, NJ Armstrong… - PloS one, 2011 - journals.plos.org
The presence of cell-free microRNAs (miRNAs) has been detected in a range of body fluids.
The miRNA content of plasma/serum in particular has been proposed as a potential source …

Normalization of circulating microRNA expression data obtained by quantitative real-time RT-PCR

F Marabita, P De Candia, A Torri… - Briefings in …, 2016 - academic.oup.com
The high-throughput analysis of microRNAs (miRNAs) circulating within the blood of healthy
and diseased individuals is an active area of biomarker research. Whereas quantitative real …

Circulating microRNAs as potential biomarkers of infectious disease

CN Correia, NC Nalpas, KE McLoughlin… - Frontiers in …, 2017 - frontiersin.org
microRNAs (miRNAs) are a class of small non-coding endogenous RNA molecules that
regulate a wide range of biological processes by post-transcriptionally regulating gene …

The impact of hemolysis on cell-free microRNA biomarkers

MB Kirschner, JJB Edelman, SCH Kao… - Frontiers in …, 2013 - frontiersin.org
Cell-free microRNAs in plasma and serum have become a promising source of biomarkers
for various diseases. Despite rapid progress in this field, there remains a lack of consensus …

Exosomal miRNAs: biological properties and therapeutic potential

G Hu, KM Drescher, XM Chen - Frontiers in genetics, 2012 - frontiersin.org
MicroRNAs (miRNAs), small non-coding regulatory RNAs that regulate gene expression at
the post-transcriptional level, are master regulators of a wide array of cellular processes …