[HTML][HTML] Protein structure-based in-silico approaches to drug discovery: Guide to COVID-19 therapeutics

Y Gupta, OV Savytskyi, M Coban, A Venugopal… - Molecular Aspects of …, 2023 - Elsevier
With more than 5 million fatalities and close to 300 million reported cases, COVID-19 is the
first documented pandemic due to a coronavirus that continues to be a major health …

Pre-admission glucagon-like peptide-1 receptor agonist (GLP-1RA) and mortality from coronavirus disease 2019 (Covid-19): A systematic review, meta-analysis, and …

TI Hariyanto, D Intan, JE Hananto, C Putri… - diabetes research and …, 2021 - Elsevier
Aims GLP-1RA has many beneficial properties, including anti-inflammatory, anti-
obesogenic, pulmonary protective effects as well as beneficial impact on gut microbiome …

[HTML][HTML] Ivermectin: a multifaceted drug of Nobel prize-honoured distinction with indicated efficacy against a new global scourge, COVID-19

AD Santin, DE Scheim, PA McCullough… - New Microbes and New …, 2021 - Elsevier
Abstract In 2015, the Nobel Committee for Physiology or Medicine, in its only award for
treatments of infectious diseases since six decades prior, honoured the discovery of …

[HTML][HTML] Repositioning Ivermectin for Covid-19 treatment: Molecular mechanisms of action against SARS-CoV-2 replication

ZY Low, AJW Yip, SK Lal - Biochimica et Biophysica Acta (BBA)-Molecular …, 2022 - Elsevier
Ivermectin (IVM) is an FDA approved macrocyclic lactone compound traditionally used to
treat parasitic infestations and has shown to have antiviral potential from previous in-vitro …

Efficacy of COVID-19 treatments: a Bayesian network meta-analysis of randomized controlled trials

C Zhang, H Jin, YF Wen, G Yin - Frontiers in Public Health, 2021 - frontiersin.org
Background: We provided a comprehensive evaluation of efficacy of available treatments for
coronavirus disease 2019 (COVID-19). Methods: We searched for candidate COVID-19 …

Acute respiratory distress syndrome and COVID-19: A literature review

M Hussain, S Khurram Syed, M Fatima… - Journal of …, 2021 - Taylor & Francis
Acute respiratory distress syndrome (ARDS) is an overwhelming inflammatory disorder of
the lung due to direct and indirect insults to the lungs. ARDS is characterized by increased …

Vitamin D supplementation and Covid‐19 outcomes: a systematic review, meta‐analysis and meta‐regression

TI Hariyanto, D Intan, JE Hananto… - Reviews in Medical …, 2022 - Wiley Online Library
Vitamin D has many protective properties and potential role against acute lung injury. Low
serum vitamin D is associated with high risk of pneumonia and development of acute …

Janus kinase (JAK)-inhibitors and coronavirus disease 2019 (Covid-19) outcomes: a systematic review and meta-analysis

RY Limen, R Sedono, A Sugiarto… - Expert Review of Anti …, 2022 - Taylor & Francis
Background Currently, JAK-inhibitors are repurposed for therapy of Covid-19 because of
their ability in restraining immune response, yet the corroboration regarding their advantage …

Delirium is a good predictor for poor outcomes from coronavirus disease 2019 (COVID-19) pneumonia: a systematic review, meta-analysis, and meta-regression

TI Hariyanto, C Putri, JE Hananto, J Arisa… - Journal of psychiatric …, 2021 - Elsevier
Aim Delirium is a common presenting symptom among older patients. Patients who
presented with delirium may have a higher morbidity and mortality rate due to older age …

Efficacy and safety of ivermectin for the treatment of COVID-19: a systematic review and meta-analysis

J Deng, F Zhou, S Ali, K Heybati, W Hou… - … Journal of Medicine, 2021 - academic.oup.com
Background Ivermectin became a popular choice for COVID-19 treatment among clinicians
and the public following encouraging results from pre-print trials and in vitro studies. Early …