Mechanisms of drug release in nanotherapeutic delivery systems
PT Wong, SK Choi - Chemical reviews, 2015 - ACS Publications
Targeted drug delivery refers to an established therapeutic strategy that develops platforms
and nanoscale devices for selective delivery of small drug molecules and therapeutic genes …
and nanoscale devices for selective delivery of small drug molecules and therapeutic genes …
PSMA-targeted radiopharmaceuticals for imaging and therapy
HJ Wester, M Schottelius - Seminars in nuclear medicine, 2019 - Elsevier
As described in more detail in other contributions in this issue of Seminars in Nuclear
Medicine, prostate-specific membrane antigen (PSMA) has become one of the most …
Medicine, prostate-specific membrane antigen (PSMA) has become one of the most …
68Ga-Complex Lipophilicity and the Targeting Property of a Urea-Based PSMA Inhibitor for PET Imaging
M Eder, M Schäfer, U Bauder-Wüst… - Bioconjugate …, 2012 - ACS Publications
Urea-based inhibitors of the prostate-specific membrane antigen (PSMA) represent low-
molecular-weight pepidomimetics showing the ability to image PSMA-expressing prostate …
molecular-weight pepidomimetics showing the ability to image PSMA-expressing prostate …
Novel Preclinical and Radiopharmaceutical Aspects of [68Ga]Ga-PSMA-HBED-CC: A New PET Tracer for Imaging of Prostate Cancer
M Eder, O Neels, M Müller, U Bauder-Wüst, Y Remde… - Pharmaceuticals, 2014 - mdpi.com
The detection of prostate cancer lesions by PET imaging of the prostate-specific membrane
antigen (PSMA) has gained highest clinical impact during the last years. 68Ga-labelled Glu …
antigen (PSMA) has gained highest clinical impact during the last years. 68Ga-labelled Glu …
2-(3-{1-Carboxy-5-[(6-[18F]Fluoro-Pyridine-3-Carbonyl)-Amino]-Pentyl}-Ureido)-Pentanedioic Acid, [18F]DCFPyL, a PSMA-Based PET Imaging Agent for Prostate …
Y Chen, M Pullambhatla, CA Foss, Y Byun… - Clinical cancer …, 2011 - AACR
Purpose: We have synthesized and evaluated in vivo 2-(3-{1-carboxy-5-[(6-[18F] fluoro-
pyridine-3-carbonyl)-amino]-pentyl}-ureido)-pentanedioic acid,[18F] DCFPyL, as a potential …
pyridine-3-carbonyl)-amino]-pentyl}-ureido)-pentanedioic acid,[18F] DCFPyL, as a potential …
Preclinical evaluation and first patient application of 99mTc-PSMA-I&S for SPECT imaging and radioguided surgery in prostate cancer
S Robu, M Schottelius, M Eiber, T Maurer… - Journal of Nuclear …, 2017 - Soc Nuclear Med
Initial studies in patients have demonstrated the suitability of 111In-PSMA-I&T (111In-
DOTAGA-(3-iodo-y)-fk-Sub (KuE))(PSMA is prostate-specific membrane antigen and I&T is …
DOTAGA-(3-iodo-y)-fk-Sub (KuE))(PSMA is prostate-specific membrane antigen and I&T is …
Linker modification strategies to control the prostate-specific membrane antigen (PSMA)-targeting and pharmacokinetic properties of DOTA-conjugated PSMA …
M Benesova, U Bauder-Wüst… - Journal of Medicinal …, 2016 - ACS Publications
Since prostate-specific membrane antigen (PSMA) is up-regulated in nearly all stages of
prostate cancer (PCa), PSMA can be considered as a viable diagnostic biomarker and …
prostate cancer (PCa), PSMA can be considered as a viable diagnostic biomarker and …
99mTc-labeled small-molecule inhibitors of prostate-specific membrane antigen for molecular imaging of prostate cancer
SM Hillier, KP Maresca, G Lu, RD Merkin… - Journal of Nuclear …, 2013 - Soc Nuclear Med
Prostate-specific membrane antigen (PSMA) is highly expressed in prostate cancer, and
small-molecule radiopharmaceuticals targeting PSMA rapidly detect the location and extent …
small-molecule radiopharmaceuticals targeting PSMA rapidly detect the location and extent …
Preclinical evaluation of novel glutamate-urea-lysine analogues that target prostate-specific membrane antigen as molecular imaging pharmaceuticals for prostate …
SM Hillier, KP Maresca, FJ Femia, JC Marquis… - Cancer research, 2009 - AACR
Prostate-specific membrane antigen (PSMA) is expressed in normal human prostate
epithelium and is highly up-regulated in prostate cancer. We previously reported a series of …
epithelium and is highly up-regulated in prostate cancer. We previously reported a series of …
Synthesis and preclinical evaluation of DOTAGA-conjugated PSMA ligands for functional imaging and endoradiotherapy of prostate cancer
M Weineisen, J Simecek, M Schottelius, M Schwaiger… - EJNMMI research, 2014 - Springer
Background Due to its high expression in prostate cancer, PSMA (prostate-specific
membrane antigen) represents an ideal target for both diagnostic imaging and …
membrane antigen) represents an ideal target for both diagnostic imaging and …