The cell microenvironment has emerged as a key determinant of cell behavior and function
in development, physiology, and pathophysiology. The extracellular matrix (ECM) within the …

Decellularization of natural tissues to produce extracellular matrix is a promising method for
three-dimensional scaffolding and for understanding microenvironment of the tissue of …

Tissue engineering is essentially a technique for imitating nature. Natural tissues are made
up of three parts: extracellular matrix (ECM), signaling systems, and cells. Therefore …

Tissue engineering and regenerative medicine involve many different artificial and biologic
materials, frequently integrated in composite scaffolds, which can be repopulated with …

The precise delivery of targeted cells through magnetic field–driven microrobots/carriers is a
promising technique for targeted therapy and tissue regeneration. This paper presents a …

Articular hyaline cartilage is extensively hydrated, but it is neither innervated nor
vascularized, and its low cell density allows only extremely limited self-renewal. Most clinical …

Articular cartilage defect repair is a problem that has long plagued clinicians. Although
mesenchymal stem cells (MSCs) have the potential to regenerate articular cartilage, they …

Hyaline cartilage is the nonlinear, inhomogeneous, anisotropic, poro-viscoelastic connective
tissue that serves as friction-reducing and load-bearing cushion in synovial joints and is vital …

Regenerative medicine approaches based on decellularized extracellular matrix (ECM)
scaffolds and tissues are rapidly expanding. The rationale for using ECM as a natural …

Background The regeneration and repair of articular cartilage remains a major challenge for
clinicians and scientists due to the poor intrinsic healing of this tissue. Since cartilage …