Nrf2 and oxidative stress in liver ischemia/reperfusion injury

R G. Bardallo, A Panisello‐Roselló… - The FEBS …, 2022 - Wiley Online Library
In response to stress signal, nuclear factor‐erythroid 2‐related factor 2 (Nrf2) induces the
expression of target genes involved in antioxidant defense and detoxification. Nrf2 activity is …

Biomarkers and utility of the antioxidant potential of probiotic Lactobacilli and Bifidobacteria as representatives of the human gut microbiota

OV Averina, EU Poluektova, MV Marsova… - Biomedicines, 2021 - mdpi.com
Lactobacilli and bifidobacteria are an important part of human gut microbiota. Among
numerous benefits, their antioxidant properties are attracting more and more attention …

The tumor microenvironment in the postsurgical liver: Mechanisms and potential targets of postoperative recurrence in human hepatocellular carcinoma

J Wu, YT Chan, Y Lu, N Wang… - Medicinal Research …, 2023 - Wiley Online Library
Surgery remains to be the mainstay of treatment for hepatocellular carcinoma (HCC).
Nonetheless, its therapeutic efficacy is significantly impaired by postoperative recurrence …

Influence of propofol‐based total intravenous anaesthesia on peri‐operative outcome measures: a narrative review

MG Irwin, CKE Chung, KY Ip, MD Wiles - Anaesthesia, 2020 - Wiley Online Library
Propofol‐based total intravenous anaesthesia is well known for its smooth, clear‐headed
recovery and anti‐emetic properties, but there are also many lesser known beneficial …

Anesthesia‐Induced Oxidative Stress: Are There Differences between Intravenous and Inhaled Anesthetics?

T Senoner, C Velik-Salchner… - … medicine and cellular …, 2021 - Wiley Online Library
Agents used for the induction of anesthesia have been shown to either promote or mitigate
oxidative stress. A fine balance between the presence of reactive oxygen species (ROS) and …

Perioperative oxidative stress: the unseen enemy

JL Stevens, M Feelisch, DS Martin - Anesthesia & Analgesia, 2019 - journals.lww.com
Reactive oxygen species (ROS) are essential for cellular signaling and physiological
function. An imbalance between ROS production and antioxidant protection results in a state …

Contribution of oxidative stress in the mechanisms of postoperative complications and multiple organ dysfunction syndrome

J Toro-Pérez, R Rodrigo - Redox Report, 2021 - Taylor & Francis
Background The extent of the damage following surgery has been subject of study for
several years. Numerous surgical complications can impact postoperative quality of life of …

Common inflammatory mechanisms in COVID-19 and Parkinson's diseases: The role of microbiome, pharmabiotics and postbiotics in their prevention

V Danilenko, A Devyatkin, M Marsova… - Journal of …, 2021 - Taylor & Francis
In the last decade, metagenomic studies have shown the key role of the gut microbiome in
maintaining immune and neuroendocrine systems. Malfunction of the gut microbiome can …

Pharmacotherapeutic potential of pratensein to avert metribuzin instigated hepatotoxicity via regulating TGF-β1, PI3K/Akt, Nrf-2/Keap-1 and NF-κB pathway

HM Hassan, M El Safadi, W Mustfa, S Tehreem… - Tissue and Cell, 2024 - Elsevier
Metribuzin (MBN) is a selective herbicide that adversely damages the vital organs of the
body including the liver. Pratensein (PTN) is a novel flavonoid that exhibits marvelous …

The mechanism of mitochondrial injury in alpha-1 antitrypsin deficiency mediated liver disease

N Khodayari, RL Wang, R Oshins, Y Lu… - International Journal of …, 2021 - mdpi.com
Alpha-1 antitrypsin deficiency (AATD) is caused by a single mutation in the SERPINA1 gene,
which culminates in the accumulation of misfolded alpha-1 antitrypsin (ZAAT) within the …