Weak Nucleophiles in the Aza‐Michael Reaction

AY Rulev - Advanced Synthesis & Catalysis, 2023 - Wiley Online Library
Abstract The 1, 4‐conjugated addition of nitrogen centered nucleophiles to electron‐
deficient alkenes is one of the most significant and widely used reactions in modern …

Phenylalanyl tRNA synthetase (PheRS) substrate mimics: design, synthesis, molecular dynamics and antimicrobial evaluation

NA Noureldin, J Richards, H Kothayer, MM Baraka… - RSC …, 2022 - pubs.rsc.org
Antimicrobial resistance is a very challenging medical issue and identifying novel
antimicrobial targets is one of the means to overcome this challenge. Phenylalanyl tRNA …

Alternative and efficient method for the preparation of 2-acetamidobenzimidazoles

AS Abdurazakov, SS Saidov… - Egyptian Journal of …, 2021 - ejchem.journals.ekb.eg
An alternative method for the synthesis of acetamidobenzimidazoles (3-6) has been
developed, including the reacylation of methylbenzimidazol-2-ylcarbamate (carbendazim …

Design, computational studies, synthesis and in vitro antimicrobial evaluation of benzimidazole based thio-oxadiazole and thio-thiadiazole analogues

NA Noureldin, J Richards, H Kothayer, MM Baraka… - BMC chemistry, 2021 - Springer
Background Two series of benzimidazole based thio-oxadiazole and thio-thiadiazole
analogues were designed and synthesised as novel antimicrobial drugs through inhibition …