Progesterone effects in the nervous system

V Theis, C Theiss - The Anatomical Record, 2019 - Wiley Online Library
The sex hormone progesterone is mainly known as a key factor in establishing and
maintaining pregnancy. In addition, progesterone has been shown to induce morphological …

Progesterone receptor-mediated actions and the treatment of central nervous system disorders: an up-date of the known and the challenge of the unknown

SL González, MF Coronel, MC Raggio, F Labombarda - Steroids, 2020 - Elsevier
Progesterone has been shown to exert a wide range of remarkable protective actions in
experimental models of central nervous system injury or disease. However, the intimate …

Current evidence for the involvement of sex steroid receptors and sex hormones in benign prostatic hyperplasia

MHA Da Silva, DB De Souza - Research and reports in urology, 2019 - Taylor & Francis
Benign prostatic hyperplasia (BPH) is a pathology that affects 50% of men over 50 years of
age and 90% of men develop BPH in their eighth decade of life. In 2018, more than 1 billion …

Intracellular progesterone receptor mediates the increase in glioblastoma growth induced by progesterone in the rat brain

L Germán-Castelán, J Manjarrez-Marmolejo… - Archives of medical …, 2016 - Elsevier
Background and Aims Progesterone (P) is a steroid hormone involved in the development of
several types of cancer including astrocytomas, the most common and malignant brain …

[HTML][HTML] Histological and gene expression analysis of the effects of menopause status and hormone therapy on the vaginal introitus and labia majora

RL Binder, MA Freedman, KB Sharma… - Journal of Clinical …, 2019 - ncbi.nlm.nih.gov
Background The study aimed to determine the effect of menopausal status and hormone
therapy on the introitus and labia majora at the levels of histology and gene expression …

[HTML][HTML] Proliferation and ovarian hormone signaling are impaired in normal breast tissues from women with BRCA1 mutations: benefit of a progesterone receptor …

L Communal, M Vilasco, J Hugon-Rodin, A Courtin… - Oncotarget, 2016 - ncbi.nlm.nih.gov
Women with inherited BRCA1 mutations have an elevated risk (40-80%) for developing
breast and ovarian cancers. Reproductive history has been reported to alter this risk …

Neurosteroids and ischemic stroke: progesterone a promising agent in reducing the brain injury in ischemic stroke

SS Andrabi, S Parvez… - Journal of Environmental …, 2017 - dl.begellhouse.com
ABSTRACT Progesterone (P4), a well-known neurosteroid, is produced by ovaries and
placenta in females and by adrenal glands in both sexes. Progesterone is also synthesized …

[HTML][HTML] 孕激素受体在非妇产科应用的研究进展

赵娜娜, 李小薇 - Advances in Clinical Medicine, 2024 - hanspub.org
孕激素是人体重要的甾体激素, 其生物学效应由多个受体介导, 包括经典的核受体PRA, PRB,
和非经典的膜受体(分为mPRα, mPRβ, mPRγ) 和孕激素受体膜组分(分为PGRMC1 …

Estradiol differentially induces progesterone receptor isoforms expression through alternative promoter regulation in a mouse embryonic hypothalamic cell line

ER Vázquez-Martínez, I Camacho-Arroyo… - Endocrine, 2016 - Springer
Progesterone receptor (PR) presents two main isoforms (PR-A and PR-B) that are regulated
by two specific promoters and transcribed from alternative transcriptional start sites. The …

[HTML][HTML] Estrogen biosynthesis in subcutaneous and visceral adipose tissue in women

N Hetemäki - 2024 - helda.helsinki.fi
Adipose tissue is an important site of steroid hormone storage, production, and metabolism.
Both the amount and distribution of adipose tissue in a female body change during a …