Margin status and survival outcomes after breast cancer conservation surgery: prospectively registered systematic review and meta-analysis

JR Bundred, S Michael, B Stuart, RI Cutress… - bmj, 2022 - bmj.com
Objective To determine if margin involvement is associated with distant recurrence and to
determine the required margin to minimise both local recurrence and distant recurrence in …

The association of surgical margins and local recurrence in women with early-stage invasive breast cancer treated with breast-conserving therapy: a meta-analysis

N Houssami, P Macaskill, M Luke Marinovich… - Annals of surgical …, 2014 - Springer
Purpose There is no consensus on what constitutes adequate negative margins in breast-
conserving therapy (BCT). We systematically review the evidence on surgical margins in …

Abbreviated course of radiotherapy (RT) for breast cancer

JD Schoenfeld, JR Harris - The Breast, 2011 - Elsevier
The use of RT as a component of breast-conserving therapy or after mastectomy has been
proven to reduce the risk of local-regional recurrence (LRR) and to improve long-term breast …

Efficacy of intraoperative entire-circumferential frozen section analysis of lumpectomy margins during breast-conserving surgery for breast cancer

T Osako, R Nishimura, Y Nishiyama, Y Okumura… - International journal of …, 2015 - Springer
Background Intraoperative frozen section analysis of the surgical margins during breast-
conserving surgery (BCS) for breast cancer can reliably achieve clear surgical margins and …

The diminishing impact of margin definitions and width on local recurrence rates following breast-conserving therapy for early-stage invasive cancer: a meta-analysis

C Shah, BP Hobbs, F Vicini, Z Al-Hilli… - Annals of Surgical …, 2020 - Springer
Background The optimal tumor-free margin definition and width following breast-conserving
therapy (BCT) for early-stage invasive cancers has been evaluated in previous meta …

Influence of surgical margins on the outcome of breast cancer patients: a retrospective analysis

S Bernardi, S Bertozzi, AP Londero, G Gentile… - World journal of …, 2014 - Springer
Objective Breast-conserving surgery has become the preferred treatment for early breast
cancer. Yet the question of what constitutes a 'safe margin', in terms of impact on patient …

Contemporary breast imaging and concordance assessment: a surgical perspective

J Landercasper, JH Linebarger - Surgical Clinics, 2011 - surgical.theclinics.com
Disease conditions of the breast and the surgery to treat them are common. The lifetime risk
for a woman to develop breast cancer is 12%. 1 Silverstein and colleagues 2 estimated that …

Hypofractionated radiotherapy for breast cancer acceleration of the START A treatment regime: intermediate tolerance and efficacy

S Janssen, C Glanzmann, S Lang, S Verlaan… - Radiation …, 2014 - Springer
Purpose Prospective evaluation of accelerated hypofractionated radiotherapy (RT) in breast
cancer patients treated with 41.6 Gy in 13 fractions plus boost delivered five times a week …

Breast cancer local therapy: what is its effect on mortality?

JR Benson, KAT Teo - World journal of surgery, 2012 - Springer
Until recently, the concept of biological predeterminism appeared pre-eminent and a worthy
successor to the Halstedian doctrine of centrifugal spread of cancer. However, evidence has …

Hypofractionated radiotherapy for breast cancer including risk-adapted boost: Update on tolerance and efficacy of an accelerated START A regime

S Janssen, C Glanzmann, S Lang, S Verlaan… - Anticancer …, 2016 - ar.iiarjournals.org
Aim: To present an update of a prospective study evaluating an accelerated
hypofractionated whole breast irradiation (WBI) schedule of the START A trial plus …