These guidelines are intended as an update to those published in the Southern African
Journal of HIV Medicine in 2014 and the update on when to initiate antiretroviral therapy in …

Methods: We used STDSIM, a stochastic microsimulation model, and developed an
approach to represent HIV prevalence and treatment coverage in 43 countries in SSA, using …

Background Expanded access to antiretroviral therapy (ART) using universal test and treat
(UTT) has been suggested as a strategy to eliminate HIV in South Africa within 7 y based on …

Tremendous progress has been made with the scale-up of antiretroviral therapy in Africa,
with an estimated seven million people now receiving antiretroviral therapy in the region …

Severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), the virus that causes
coronavirus disease 2019 (COVID‐19), has shifted our paradigms about B cell immunity and …

Abstract Background South Africa has the largest public antiretroviral therapy (ART)
programme in the world. We assessed temporal trends in pretreatment HIV-1 drug …

Background. Transmitted human immunodeficiency virus type 1 (HIV) drug resistance (TDR)
mutations are transmitted from nonresponding patients (defined as patients with no initial …

Transmission of drug-resistant pathogens presents an almost-universal challenge for
fighting infectious diseases. Transmitted drug resistance mutations (TDRM) can persist in …

Background HIV drug resistance (HIVDR) testing was included in the 2017 South African
national HIV household survey. We describe the prevalence of HIVDR by drug class, age …

Objective To determine the frequency and patterns of acquired antiretroviral drug resistance
in a rural primary health care programme in South Africa. Design Cross-sectional study …