The immune and nervous systems have unique developmental trajectories that individually
build intricate networks of cells with highly specialized functions. These two systems have …

Interleukin-6 (IL-6) is an acknowledged inflammatory cytokine with a pleiotropic action,
mediating innate and adaptive immunity and multiple physiological processes, including …

Importance Previous in vitro and postmortem research suggests that inflammation may lead
to structural brain changes via activation of microglia and/or astrocytic dysfunction in a range …

Schizophrenia is a disorder with a heterogeneous etiology involving complex interplay
between genetic and environmental risk factors. The immune system is now known to play …

Several lines of evidence support the link between maternal inflammation during pregnancy
and increased likelihood of neurodevelopmental and psychiatric disorders in offspring. This …

The impact of infections and inflammation during pregnancy on the developing fetal brain
remains incompletely defined, with important clinical and research gaps. Although the …

Autism spectrum disorder (ASD) is a group of complex multifactorial neurodevelopmental
disorders characterized by a wide and variable set of neuropsychiatric symptoms, including …

Inflammatory mediators affect the brain during development. Neurodevelopmental disorders
such as autism spectrum disorders, cognitive impairment, cerebral palsy, epilepsy, and …

Autism spectrum disorder (ASD) has captured the attention of scientists, clinicians and the
lay public because of its uncertain origins and striking and unexplained clinical …

The developing brain is sensitive to a variety of insults. Epidemiological studies have
identified prenatal exposure to infection as a risk factor for a range of neurological disorders …