[HTML][HTML] The Minderoo-Monaco Commission on plastics and human health

PJ Landrigan, H Raps, M Cropper, C Bald… - Annals of Global …, 2023 - ncbi.nlm.nih.gov
Background: Plastics have conveyed great benefits to humanity and made possible some of
the most significant advances of modern civilization in fields as diverse as medicine …

Phthalate toxicity mechanisms: An update

CG Sree, V Buddolla, BA Lakshmi, YJ Kim - Comparative Biochemistry and …, 2023 - Elsevier
Phthalates are one of the most widely used plasticizers in polymer products, and they are
increasingly being exposed to people all over the world, generating health concerns …

[HTML][HTML] Di-(2-ethylhexyl) phthalate substitutes accelerate human adipogenesis through PPARγ activation and cause oxidative stress and impaired metabolic …

A Schaffert, I Karkossa, E Ueberham… - Environment …, 2022 - Elsevier
The obesity pandemic is presumed to be accelerated by endocrine disruptors such as
phthalate-plasticizers, which interfere with adipose tissue function. With the restriction of the …

[HTML][HTML] Structural basis of the activation of PPARγ by the plasticizer metabolites MEHP and MINCH

A Useini, F Engelberger, G Künze, N Sträter - Environment International, 2023 - Elsevier
Abstract Di-2-ethylhexyl phthalate (DEHP) and its substitute 1, 2-cyclohexane dicarboxylic
acid diisononyl ester (DINCH) are widely used as plasticizers but may have adverse health …

Genotoxicity of organic contaminants in the soil: A review based on bibliometric analysis and methodological progress

M Han, Z Zhang, S Liu, Y Sheng, MG Waigi, X Hu… - Chemosphere, 2023 - Elsevier
Organic contaminants (OCs) are ubiquitous in the environment, posing severe threats to
human health and ecological balance. In particular, OCs and their metabolites could interact …

The role of endocrine disruptors bisphenols and phthalates in obesity: current evidence, perspectives and controversies

M Dalamaga, D Kounatidis, D Tsilingiris… - International Journal of …, 2024 - mdpi.com
Excess body weight constitutes one of the major health challenges for societies and
healthcare systems worldwide. Besides the type of diet, calorie intake and the lack of …

Exposure trends to the non-phthalate plasticizers DEHTP, DINCH, and DEHA in children from 2012 to 2017: the Hokkaido study

RM Ketema, M Kasper-Sonnenberg… - Environmental …, 2023 - ACS Publications
Phthalates owing to their endocrine-disrupting effects are regulated in certain products,
leading to their replacement with substitutions such as di-2-ethylhexyl terephthalate …

Protective effect of rutin on triethylene glycol dimethacrylate-induced toxicity through the inhibition of caspase activation and reactive oxygen species generation in …

LC Yang, YC Chang, KL Yeh, FM Huang… - International Journal of …, 2022 - mdpi.com
Rutin, also called quercetin-3-rhamnosyl glucoside, is a natural flavonol glycoside present in
many plants. Rutin is used to treat various diseases, such as inflammation, diabetes, and …

Rebuttal to comment on “alternative plasticizers as emerging global environmental and health threat: another regrettable substitution?” focus on DINCH as an …

A Qadeer, KL Kirsten, Z Ajmal… - Environmental Science & …, 2022 - ACS Publications
In 2015, The European Commission tasked the Scientific Committee on Emerging and
Newly-Identified Health Risks (SCENIHR) to revise its 2008 opinion on medical devices …

Phthalates mixture on allergies and oxidative stress biomarkers among children: The Hokkaido study

RM Ketema, YA Bamai, C Miyashita, T Saito… - Environment …, 2022 - Elsevier
Background Exposure to individual phthalates and the mediation effect of oxidative stress in
association with asthma and allergic symptoms have been studied previously. Little is …