Neuropeptide Y: the universal soldier

T Pedrazzini, F Pralong, E Grouzmann - Cellular and Molecular Life …, 2003 - Springer
The peptidic neurotransmitter neuropeptide Y (NPY) has received great attention because it
has been implicated in the regulation of several organ systems. In particular, NPY is …

The role of NPY in hypothalamic mediated food intake

RE Mercer, MJS Chee, WF Colmers - Frontiers in neuroendocrinology, 2011 - Elsevier
Neuropeptide Y (NPY) is a highly conserved neuropeptide with orexigenic actions in
discrete hypothalamic nuclei that plays a role in regulating energy homeostasis. NPY …

Neuropeptide Y and neuropeptide Y receptor subtypes in brain and peripheral tissues

Y Dumont, JC Martel, A Fournier, S St-Pierre… - Progress in …, 1992 - Elsevier
8.2. Effects in the pancreas 8.3. Effects on the intestinal sphincter 8.4. Effects on intestinal
motility 8.5. Effects on intestinal cellular proliferation 8.6. Effects on intestinal fluid and ion …

Structural diversity of receptors for neuropeptide Y, peptide YY and pancreatic polypeptide

D Larhammar - Regulatory peptides, 1996 - Elsevier
The NPY (neuropeptide Y) family of neuroendocrine peptides consists of NPY, PYY (peptide
YY) and PP (pancreatic polypeptide). Several receptors have been characterized …

Effects of neuropeptide Y on the electrical properties of neurons

WF Colmers, D Bleakman - Trends in neurosciences, 1994 - cell.com
Neurop@ tide Y, one or the scions of the pancreatic" polyp@ tide. family, is tbund throughout
the nervous system. Based on its abundance alone, one would expect neuropeptide Y to …

Neuropeptide Y and its receptors as potential therapeutic drug targets

AP Silva, C Cavadas, E Grouzmann - Clinica Chimica Acta, 2002 - Elsevier
Neuropeptide Y (NPY) is a 36-amino-acid peptide that exhibits a large number of
physiological activities in the central and peripheral nervous systems. NPY mediates its …

Receptors for neuropeptide Y: multiple subtypes and multiple second messengers

MC Michel - Trends in pharmacological sciences, 1991 - cell.com
Neuropeptide Y (NPYI is a 36 amino acid peptide which was fimtisolakdin1982fromporcine
bmin. Itbelongstothe'~ family of stMurally related peptides (named after one member …

Neuropeptide Y induces migration, proliferation, and tube formation of endothelial cells bimodally via Y1, Y2, and Y5 receptors

S Movafagh, JP Hobson, S Spiegel… - The FASEB …, 2006 - Wiley Online Library
Previously we discovered that NPY induces ischemic angiogenesis by activating Y2 and Y5
receptors. The receptors that mediate specific steps of the complex process of angiogenesis …

The role of neuropeptide Y in cardiovascular regulation

P Walker, E Grouzmann, M Burnier… - Trends in pharmacological …, 1991 - cell.com
Neumpeptidc Y (NPYJ is a 36 amino acid prptide present in the brain, the adrenal medulla
and peripheral sympathetic nerves. The localization and mode of release of NPY led to the …

Autoradiographic distribution of [125I]Leu31,Pro34]PYY and [125I]PYY3–36 binding sites in the rat brain evaluated with two newly developed Y1 and Y2 …

Y Dumont, A Fournier, S St‐Pierre, R Quirion - Synapse, 1996 - Wiley Online Library
The peptide YY derivatives [Leu3l, Pro3* 1PYY and Pm3-36 are highly selective Y1 and Y2
agonists, devoid of activity on the Y3 receptor subtype [Dumont et al.(1994) Molec. Brain …