The amazing potential of fungi: 50 ways we can exploit fungi industrially

KD Hyde, J Xu, S Rapior, R Jeewon, S Lumyong… - Fungal Diversity, 2019 - Springer
Fungi are an understudied, biotechnologically valuable group of organisms. Due to the
immense range of habitats that fungi inhabit, and the consequent need to compete against a …

Cytochrome P450 enzymes in fungal natural product biosynthesis

X Zhang, J Guo, F Cheng, S Li - Natural Product Reports, 2021 - pubs.rsc.org
Covering: 2015 to the end of 2020 Fungal-derived polyketides, non-ribosomal peptides,
terpenoids and their hybrids contribute significantly to the chemical space of total natural …

101 Dothideomycetes genomes: a test case for predicting lifestyles and emergence of pathogens

S Haridas, R Albert, M Binder, J Bloem… - Studies in …, 2020 - ingentaconnect.com
Dothideomycetes is the largest class of kingdom Fungi and comprises an incredible diversity
of lifestyles, many of which have evolved multiple times. Plant pathogens represent a major …

Biologically active secondary metabolites from the fungi

GF Bills, JB Gloer - Microbiology spectrum, 2016 - Am Soc Microbiol
Many Fungi have a well-developed secondary metabolism. The diversity of fungal species
and the diversification of biosynthetic gene clusters underscores a nearly limitless potential …

Atlas of nonribosomal peptide and polyketide biosynthetic pathways reveals common occurrence of nonmodular enzymes

H Wang, DP Fewer, L Holm… - Proceedings of the …, 2014 - National Acad Sciences
Nonribosomal peptides and polyketides are a diverse group of natural products with
complex chemical structures and enormous pharmaceutical potential. They are synthesized …

Traversing the fungal terpenome

MB Quin, CM Flynn, C Schmidt-Dannert - Natural product reports, 2014 - pubs.rsc.org
Covering: 1965–2014 Fungi (Ascomycota and Basidiomycota) are prolific producers of
structurally diverse terpenoid compounds. Classes of terpenoids identified in fungi include …

The birth, evolution and death of metabolic gene clusters in fungi

A Rokas, JH Wisecaver, AL Lind - Nature Reviews Microbiology, 2018 - nature.com
Fungi contain a remarkable diversity of both primary and secondary metabolic pathways
involved in ecologically specialized or accessory functions. Genes in these pathways are …

Translating biosynthetic gene clusters into fungal armor and weaponry

NP Keller - Nature chemical biology, 2015 - nature.com
Filamentous fungi are renowned for the production of a diverse array of secondary
metabolites (SMs) where the genetic material required for synthesis of a SM is typically …

A review of the mechanism of action of cyclosporine A: the role of cyclosporine A in dry eye disease and recent formulation developments

LM Periman, FS Mah, PM Karpecki - Clinical Ophthalmology, 2020 - Taylor & Francis
Dry eye disease (DED) is a multifactorial disease of the ocular surface and tear film that has
gained awareness as a public health problem. Characteristics of DED include tear film …

Biosynthetic gene clusters and the evolution of fungal chemodiversity

A Rokas, ME Mead, JL Steenwyk, HA Raja… - Natural product …, 2020 - pubs.rsc.org
Covering: up to 2019 Fungi produce a remarkable diversity of secondary metabolites: small,
bioactive molecules not required for growth but which are essential to their ecological …