Large biomolecular systems are at the heart of many essential cellular processes. The
dynamics and energetics of an increasing number of these systems are being studied by …

A DNA molecule is under continuous influence of endogenous and exogenous damaging
factors, which produce a variety of DNA lesions. Apurinic/apyrimidinic sites (abasic or AP …

The features of previously unexplored labile complexes of human 40S ribosomal subunits
with RNAs, whose formation is manifested in the cross-linking of aldehyde derivatives of …

Abstract The nitroxide TPA (2, 2, 5, 5‐tetramethyl‐pyrrolin‐1‐oxyl‐3‐acetylene) is an
excellent spin label for EPR studies of RNA. Previous synthetic methods, however, are …

The binding of G-quadruplex structures (G4s) with photosensitizers is of considerable
importance in medicinal chemistry and drug discovery due to their promising potential in …

Paramagnetic (open-shell) systems, including transition metal ions, radical intermediates
and defect centres, are often involved in catalytic transformations. Despite the prevalence of …

N-oxyl radicals are well known as one of the richest classes of long-living free radicals. They
are widely used as redox catalysts, mediators of living polymerization, contrast reagents for …

The emergence of systems biology in the post-genomic era has led to investigating
increasingly complex macromolecular assemblies, emphasising holistic approaches in …

The conformation of mRNA in the region of the human 80S ribosome decoding site was
monitored using 11-mer mRNA analogues that bore nitroxide spin labels attached to the …

Summary Electron Paramagnetic Resonance (EPR) spectroscopy is a powerful method to
get insight into the structures and dynamics of RNA. In order to be applicable, the RNA …