Hippo signaling in the ovary: emerging roles in development, fertility, and disease

KL Clark, JW George, E Przygrodzka… - Endocrine …, 2022 - academic.oup.com
Emerging studies indicate that the Hippo pathway, a highly conserved pathway that
regulates organ size control, plays an important role in governing ovarian physiology …

The role of Hippo pathway in ovarian development

M Zhu, M Xu, J Zhang, C Zheng - Frontiers in Physiology, 2023 - frontiersin.org
The follicle is the functional unit of the ovary, whereby ovarian development is largely
dependent on the development of the follicles themselves. The activation, growth, and …

Transcriptome comparative analysis of ovarian follicles reveals the key genes and signaling pathways implicated in hen egg production

X Sun, X Chen, J Zhao, C Ma, C Yan, S Liswaniso… - Bmc Genomics, 2021 - Springer
Background Ovarian follicle development plays an important role in determination of poultry
egg production. The follicles at the various developmental stages possess their own distinct …

Molecular mechanism of apoptosis induced by 4-tBP in common carp (Cyprinus carpio L.) head kidneys was explored from various angles: Hippo pathway, miR-203a …

J Liang, X Lin, C Jiang, Y Liu, Z Hao, M Qiu, X Liu… - Aquaculture, 2024 - Elsevier
tert butylphenol (4-tBP), a toxic environmental pollutant estrogen, received widespread
attention due to its widespread presence, environmental persistence, and toxic effect …

Yes-associated protein 1 is required for proliferation and function of bovine granulosa cells in vitro

MR Plewes, X Hou, P Zhang, A Liang… - Biology of …, 2019 - academic.oup.com
Abstract Yes-associated protein 1 (YAP1) is a major component of the Hippo signaling
pathway. Although the exact extracellular signals that control the Hippo pathway are …

Interacting networks of the hypothalamic–pituitary–ovarian axis regulate layer hens performance

J Zhao, H Pan, Y Liu, Y He, H Shi, C Ge - Genes, 2023 - mdpi.com
Egg production is a vital biological and economic trait for poultry breeding. The
'hypothalamic–pituitary–ovarian (HPO) axis' determines the egg production, which affects …

Transcription profiles of age-at-maturity-associated genes suggest cell fate commitment regulation as a key factor in the Atlantic salmon maturation process

J Kurko, PV Debes, AH House, T Aykanat… - G3: Genes …, 2020 - academic.oup.com
Despite recent taxonomic diversification in studies linking genotype with phenotype, follow-
up studies aimed at understanding the molecular processes of such genotype-phenotype …

Candidate genes associated with economically important traits in dairy goats

M Getaneh, K Alemayehu - Cogent Food & Agriculture, 2022 - Taylor & Francis
Goats are important livestock species worldwide, due to their valuable commodities,
including meat, milk, dairy products, fleece, and skin. Most of the economically important …

Inhibitory effect of SLIT2 on granulosa cell proliferation mediated by the CDC42-PAKs-ERK1/2 MAPK pathway in the prehierarchical follicles of the chicken ovary

R Xu, N Qin, X Xu, X Sun, X Chen, J Zhao - Scientific Reports, 2018 - nature.com
The SLIT2 ligand and ROBO receptors of the SLIT/ROBO pathway are expressed in hen
ovarian follicles and have been shown to play critical roles in ovary development, cell …

Vgll3 and the Hippo pathway are regulated in Sertoli cells upon entry and during puberty in Atlantic salmon testis

E Kjærner-Semb, F Ayllon, L Kleppe, E Sørhus… - Scientific Reports, 2018 - nature.com
Vgll3 is linked to age at maturity in Atlantic salmon (Salmo salar). However, the molecular
mechanisms involving Vgll3 in controlling timing of puberty as well as relevant tissue and …