[HTML][HTML] Caveolin-3 and arrhythmias: insights into the molecular mechanisms

M He, J Qiu, Y Wang, Y Bai, G Chen - Journal of Clinical Medicine, 2022 - mdpi.com
Caveolin-3 is a muscle-specific protein on the membrane of myocytes correlated with a
variety of cardiovascular diseases. It is now clear that the caveolin-3 plays a critical role in …

Protein phosphatase 2A in the healthy and failing heart: New insights and therapeutic opportunities

NM Sergienko, DG Donner, LMD Delbridge… - Cellular …, 2022 - Elsevier
Protein phosphatases have emerged as critical regulators of phosphoprotein homeostasis in
settings of health and disease. Protein phosphatase 2A (PP2A) encompasses a large …

[HTML][HTML] Assembly of a heptameric STRIPAK complex is required for coordination of light-dependent multicellular fungal development with secondary metabolism in …

N Elramli, B Karahoda, Ö Sarikaya-Bayram… - PLoS …, 2019 - journals.plos.org
Eukaryotic striatin forms striatin-interacting phosphatase and kinase (STRIPAK) complexes
that control many cellular processes including development, cellular transport, signal …

[HTML][HTML] Striatins and STRIPAK complex partners in clinical outcomes of patients with breast cancer and responses to drug treatment

AX Li, JJ Zeng, TA Martin, L Ye, F Ruge… - Chinese Journal of …, 2023 - ncbi.nlm.nih.gov
Objective Striatins (STRNs) family, which contains three multi-domain scaffolding proteins,
are cornerstones of the striatins interacting phosphatase and kinase (STRIPAK) complex …

[HTML][HTML] Unsupervised ensemble-based phenotyping enhances discoverability of genes related to left-ventricular morphology

R Bonazzola, E Ferrante, N Ravikumar, Y Xia… - Nature Machine …, 2024 - nature.com
Recent genome-wide association studies have successfully identified associations between
genetic variants and simple cardiac morphological parameters derived from cardiac …

Striatin plays a major role in angiotensin II-induced cardiomyocyte and cardiac hypertrophy in mice in vivo

JJ Cull, STE Cooper, HO Alharbi, SP Chothani… - Clinical …, 2024 - portlandpress.com
The three striatins (STRN, STRN3, STRN4) form the core of STR iatin-I nteracting P
hosphatase and K inase (STRIPAK) complexes. These place protein phosphatase 2A …

Therapeutic potential of miR-21 regulation by human peripheral blood derived-small extracellular vesicles in myocardial infarction

JY Kang, H Kim, D Mun, N Yun, B Joung - Clinical Science, 2020 - portlandpress.com
Small extracellular vesicles (sEVs) as natural membranous vesicles are on the frontiers of
nanomedical research, due to their ability to deliver therapeutic molecules such as …

The SLMAP/Striatin complex: An emerging regulator of normal and abnormal cardiac excitation-contraction coupling

M Nader - European Journal of Pharmacology, 2019 - Elsevier
The excitation-contraction (EC) module involves a harmonized correspondence between the
sarcolemma and the sarcoplasmic reticulum. This is provided by membrane proteins, which …

Unsupervised ensemble-based phenotyping helps enhance the discoverability of genes related to heart morphology

R Bonazzola, E Ferrante, N Ravikumar, Y Xia… - arXiv preprint arXiv …, 2023 - arxiv.org
Recent genome-wide association studies (GWAS) have been successful in identifying
associations between genetic variants and simple cardiac parameters derived from cardiac …

[HTML][HTML] 17β-Estradiol upregulates striatin protein levels via Akt pathway in human umbilical vein endothelial cells

S Zheng, P Sun, H Liu, R Li, L Long, Y Xu, S Chen… - PLoS …, 2018 - journals.plos.org
17β-estradiol (E2) has been shown to have beneficial effects on the cardiovascular system.
We previously demonstrated that E2 increases striatin levels and inhibits migration in …