The therapeutic potential of natural products for treating pancreatic cancer

X He, N Wang, Y Zhang, X Huang… - Frontiers in …, 2022 - frontiersin.org
Pancreatic cancer is one of the most malignant tumors of the digestive tract, with the poor
prognosis and low 5-year survival rate less than 10%. Although surgical resection and …

Metabolic pathways regulating colorectal cancer: A potential therapeutic approach

N Zafari, M Velayati, S Damavandi… - Current …, 2022 - ingentaconnect.com
Colorectal cancer (CRC) is one of the most prevalent cancers globally. Despite recent
progress in identifying etiologies and molecular genetics as well as new therapeutic …

Antitumor effect and gut microbiota modulation by quercetin, luteolin, and xanthohumol in a rat model for colorectal cancer prevention

Á Pérez-Valero, P Magadán-Corpas, S Ye… - Nutrients, 2024 - mdpi.com
Colorectal cancer stands as the third most prevalent form of cancer worldwide, with a
notable increase in incidence in Western countries, mainly attributable to unhealthy dietary …

Roles of Phytochemicals in Cancer Prevention and Therapeutics

DG Pons - International journal of molecular sciences, 2024 - mdpi.com
This Special Issue focused on the importance of phytochemicals for their use in the
prevention and treatment of cancer. The impact of publications about the effects of …

Effect of Xanthohumol, a Bioactive Natural Compound from Hops, on Adenosine Pathway in Rat C6 Glioma and Human SH-SY5Y Neuroblastoma Cell Lines

A Tejero, DA León-Navarro, M Martín - Nutrients, 2024 - mdpi.com
Xanthohumol (Xn) is an antioxidant flavonoid mainly extracted from hops (Humulus lupulus),
one of the main ingredients of beer. As with other bioactive compounds, their therapeutic …

[HTML][HTML] Xanthohumol, a prenylated flavonoid from hops (Humulus lupulus L.) exerts multidirectional pro-healing properties towards damaged zebrafish hair cells by …

N Kasica, J Kaleczyc - Toxicology and Applied Pharmacology, 2024 - Elsevier
Xanthohumol (XN) is a prominent prenylated flavonoid present in the hop plant (Humulus
lupulus L.). Despite undoubted pro-healing properties of hop plant, there is still a need for …

The advances of broad-spectrum and hot anti-coronavirus drugs

S Zeng, Y Li, W Zhu, Z Luo, K Wu, X Li, Y Fang, Y Qin… - Microorganisms, 2022 - mdpi.com
Coronaviruses, mainly including severe acute respiratory syndrome virus, severe acute
respiratory syndrome coronavirus 2, Middle East respiratory syndrome virus, human …

Efficient glycosylation and in vitro Neuroprotective Evaluation of abundant prenylflavonoid in Hops

W Ji, L Zhao, C Yun, J Liu, J Ma, L Zhu, J Duan… - Process …, 2024 - Elsevier
Structurally unique isopentenyl flavonoids are extremely low in natural plant species, and
their cumbersome chemical pathways, scarcity of donors, and poor stability have severely …

Development of necroptosis-related gene signature to predict the prognosis of colon adenocarcinoma

M Li, T Zhang, W Chen - Frontiers in Genetics, 2022 - frontiersin.org
Colon adenocarcinoma (COAD) is a common malignancy and has a high mortality rate.
However, the current tumor node metastasis (TNM) staging system is inadequate for …

Xanthohumol Suppresses Endometrial Cancer Cell Proliferation via Promotion of Smurf1-mediated ACLY Ubiquitination and Degradation

C Hu, M Yang, J Xu, J Tian, T Zhang, A Abulizi, J Zhang… - 2024 - researchsquare.com
ATP citrate lyase (ACLY) is pivotal in de novo fatty acid synthesis. It emerges as a core
metabolic enzyme implicated in malignant tumor progression, especially in Endometrial …