The survival, proliferation, self-renewal and differentiation of human pluripotent stem cells
(hPSCs, including human embryonic stem cells and human induced pluripotent stem cells) …

Background: Advancing structural and functional maturation of stem cell–derived
cardiomyocytes remains a key challenge for applications in disease modeling, drug …

Human pluripotent stem cell (hPSC)-derived kidney organoids may facilitate disease
modeling and the generation of tissue for renal replacement. Long-term application …

Recent years, cell-based therapeutics are undergoing explosive growth in the modern
biomedical field. The ability for non-invasively and real-timely tracking and understanding …

Transplantation of human embryonic stem cells (hESC) into immune-deficient mice leads to
the formation of differentiated tumors comprising all three germ layers, resembling …

Recent withdrawals of prescription drugs from clinical use because of unexpected side
effects on the heart have highlighted the need for more reliable cardiac safety pharmacology …

The derivation of human embryonic stem (hES) cells has opened new avenues for studies
on human development and provided a potential source of cells for replacement therapy. To …

Regeneration of the myocardium by transplantation of cardiomyocytes is an emerging
therapeutic strategy. Human embryonic stem cells (HESC) form cardiomyocytes readily but …

In order to promote the uniform and reproducible differentiation of human embryonic stem
cells (HESCs) in response to exogenously added growth factors, we have developed a …

To realize the therapeutic potential of human embryonic stem cells (hESCs), it is necessary
to regulate their differentiation in a uniform and reproducible manner. We have developed a …