Background Hsp90 is an environmentally contingent molecular chaperone that influences
the form and function of diverse regulators of cellular signaling. Hsp90 potentiates the …

Significant advances have been made in our understanding of heat shock protein 90
(Hsp90) in terms of its structure, biochemical characteristics, post-translational modifications …

Geldanamycin (GDM) has been modified by different type neutral/acidic/basic substituents
(1–7) and by quinuclidine motif (8), transformed into ammonium salts (9–13) at C (17) …

Entamoeba histolytica and Giardia lamblia are anaerobic protozoan parasites that cause
amebiasis and giardiasis, two of the most common diarrheal diseases worldwide. Current …

Although adaptive metal tolerance may arise in fungal populations in polluted soils, the
mechanisms underlying metal-specific tolerance are poorly understood. Comparative …

Heat shock protein 90 participates in diverse biological processes ranging from protein
folding, cell cycle, signal transduction and development to evolution in all eukaryotes. It is …

SUMMARY 1 Hypoxia‐induced cardiomyocyte apoptosis contributes significantly to cardiac
dysfunction following trauma, shock and burn injury. There is evidence that heat shock …

The involvement of Hsp90 in progression of diseases like cancer, neurological disorders
and several pathogen related conditions is well established. Hsp90, therefore, has emerged …

Background Hsp90 from Giardia lamblia is expressed by splicing of two independently
transcribed RNA molecules, coded by genes named HspN and HspC located 777 kb apart …

Heat-shock protein 90 (Hsp90) is an ATP-dependent molecular chaperone that is essential
for the normal functioning of eukaryotic cells. It plays crucial roles in cell signalling, cell-cycle …