Progress in the field of precision medicine has changed the landscape of cancer therapy.
Precision medicine is propelled by technologies that enable molecular profiling, genomic …

Over the last three decades, polymeric micelles have emerged as a highly promising drug
delivery platform for therapeutic compounds. Particularly, poorly soluble small molecules …

Cardiovascular diseases comprise of non-communicable disorders that involve the heart
and/or blood vessels and have become the leading cause of death worldwide with …

Autophagy modulation is considered to be a promising programmed cell death mechanism
to prevent and cure a great number of disorders and diseases. The crucial step in designing …

Respiratory disorders are among the most important medical problems threatening human
life. The conventional therapeutics for respiratory disorders are hindered by insufficient drug …

Nanoparticles are exclusively suitable for studying and developing potential therapies
against cardiovascular diseases (CVD) because of their size, fine-tunable properties, and …

Pulmonary arterial hypertension (PAH) is a progressive and fatal disease without a cure.
The exact pathogenic mechanisms of PAH are complex and poorly understood, yet a …

Over the past few decades, enhanced permeability of tumor vasculature was actively
exploited for targeted delivery of anticancer nanomedicines resulting in numerous …

Highlights•Nanomedicine has emerged as a field with great opportunities to improve
treatment strategies.•Pulmonary arterial hypertension (PAH) is a serious and incurable …

With the non-selective vasodilating action, short half-life and first-pass metabolism of
sildenafil (SC), local application in the lung for pulmonary arterial hypertension is of high …