HIV-1 Tat and viral latency: what we can learn from naturally occurring sequence variations
D Kamori, T Ueno - Frontiers in microbiology, 2017 - frontiersin.org
Despite the effective use of antiretroviral therapy, the remainder of a latently HIV-1-infected
reservoir mainly in the resting memory CD4+ T lymphocyte subset has provided a great …
reservoir mainly in the resting memory CD4+ T lymphocyte subset has provided a great …
[HTML][HTML] Strategies for bispecific single chain antibody in cancer immunotherapy
S Zhou, J Wei, S Su, F Chen, Y Qiu, B Liu - Journal of Cancer, 2017 - ncbi.nlm.nih.gov
Genetic engineering has resulted in more than 50 recombinant bispecific antibody formats
over the past two decades. Bispecific scFv antibodies represent a successful and promising …
over the past two decades. Bispecific scFv antibodies represent a successful and promising …
HIV-1 subtype C Tat exon-1 amino acid residue 24K is a signature for neurocognitive impairment
Variation and differential selection pressures on Tat genes have been shown to alter the
biological function of the protein, resulting in pathological consequences in a number of …
biological function of the protein, resulting in pathological consequences in a number of …
Molecular and genetic characterization of HIV-1 Tat exon-1 gene from cameroon shows conserved Tat HLA-binding epitopes: Functional implications
G Teto, JY Fonsah, CT Tagny, D Mbanya, E Nchindap… - Viruses, 2016 - mdpi.com
HIV-1 Tat plays a critical role in viral transactivation. Subtype-B Tat has potential use as a
therapeutic vaccine. However, viral genetic diversity and population genetics would …
therapeutic vaccine. However, viral genetic diversity and population genetics would …
Evolutionary dynamics of Tat in HIV-1 subtypes B and C
Evolutionary characteristics of HIV-1 have mostly studied focusing its structural genes, Gag,
Pol and Env. However, regarding the process of HIV-1's evolution, few studies emphasize …
Pol and Env. However, regarding the process of HIV-1's evolution, few studies emphasize …
The evolving profile of the signature amino acid residues in HIV-1 subtype C tat
SPG Aralaguppe, S Sharma, M Menon… - AIDS Research and …, 2016 - liebertpub.com
Using several HIV-1 tat exon 1 amino acid sequences available from public databases and
additional sequences derived from a southern Indian clinical cohort, we compared the …
additional sequences derived from a southern Indian clinical cohort, we compared the …
A novel, sensitive dual-indicator cell line for detection and quantification of inducible, replication-competent latent HIV-1 from reservoir cells
Understanding the mechanisms involved in HIV infection and latency, and development of a
cure, rely on the availability of sensitive research tools such as indicator cells, which allow …
cure, rely on the availability of sensitive research tools such as indicator cells, which allow …
[PDF][PDF] Studio della risposta immunitaria umorale anti-Tat in soggetti HIV-1 positivi
SSD BIO, M MAGNANI, A MARIAROSARIA - ora.uniurb.it
The Tat regulatory protein of human immunodeficiency virus type 1 (HIV-1) plays a key role
in viral infectivity and HIV-1 infection progression to AIDS. In natural infection, Tat represents …
in viral infectivity and HIV-1 infection progression to AIDS. In natural infection, Tat represents …
[PDF][PDF] Studio della risposta immunitaria umorale anti-Tat in soggetti HIV-1 positivi
A Cangiano - 2016 - tesidottorato.depositolegale.it
The Tat regulatory protein of human immunodeficiency virus type 1 (HIV-1) plays a key role
in viral infectivity and HIV-1 infection progression to AIDS. In natural infection, Tat represents …
in viral infectivity and HIV-1 infection progression to AIDS. In natural infection, Tat represents …