Basic mechanisms of diabetic heart disease

RH Ritchie, ED Abel - Circulation research, 2020 - Am Heart Assoc
Diabetes mellitus predisposes affected individuals to a significant spectrum of
cardiovascular complications, one of the most debilitating in terms of prognosis is heart …

Dietary advanced glycation end‐products: Perspectives linking food processing with health implications

Q Zhang, Y Wang, L Fu - … Reviews in Food Science and Food …, 2020 - Wiley Online Library
Dietary advanced glycation end products (dAGEs) are complex and heterogeneous
compounds derived from nonenzymatic glycation reactions during industrial processing and …

Advanced glycation endproducts in food and their effects on health

MW Poulsen, RV Hedegaard, JM Andersen… - Food and Chemical …, 2013 - Elsevier
Advanced glycation endproducts (AGEs) form by Maillard-reactions after initial binding of
aldehydes with amines or amides in heated foods or in living organisms. The mechanisms of …

Inflammation and metabolic cardiomyopathy

K Nishida, K Otsu - Cardiovascular research, 2017 - academic.oup.com
Excessive feeding is associated with an increase in the incidence of chronic metabolic
diseases, such as obesity, insulin resistance, and type 2 diabetes. Metabolic disturbance …

Cellular signalling of the receptor for advanced glycation end products (RAGE)

J Xie, JD Méndez, V Méndez-Valenzuela… - Cellular signalling, 2013 - Elsevier
The receptor for advanced glycation end-product (RAGE) is the signal transduction receptor
which senses a variety of signalling molecules including advanced glycation end products …

[HTML][HTML] The diabetic cardiomyopathy: the contributing pathophysiological mechanisms

T Salvatore, PC Pafundi, R Galiero, G Albanese… - Frontiers in …, 2021 - frontiersin.org
Individuals with diabetes mellitus (DM) disclose a higher incidence and a poorer prognosis
of heart failure (HF) than non-diabetic people, even in the absence of other HF risk factors …

[HTML][HTML] Vascular effects of advanced glycation endproducts: clinical effects and molecular mechanisms

A Stirban, T Gawlowski, M Roden - Molecular metabolism, 2014 - Elsevier
The enhanced generation and accumulation of advanced glycation endproducts (AGEs)
have been linked to increased risk for macrovascular and microvascular complications …

[HTML][HTML] Inflammation in metabolic cardiomyopathy

FA Wenzl, S Ambrosini, SA Mohammed… - Frontiers in …, 2021 - frontiersin.org
Overlapping pandemics of lifestyle-related diseases pose a substantial threat to
cardiovascular health. Apart from coronary artery disease, metabolic disturbances linked to …

[HTML][HTML] Of mice and men: models and mechanisms of diabetic cardiomyopathy

C Riehle, J Bauersachs - Basic research in cardiology, 2019 - Springer
Diabetes mellitus increases the risk of heart failure independent of co-existing hypertension
and coronary artery disease. Although several molecular mechanisms for the development …

An overview of the crosstalk between inflammatory processes and metabolic dysregulation during diabetic cardiomyopathy

X Palomer, L Salvadó, E Barroso… - International journal of …, 2013 - Elsevier
Metabolic disorders such as obesity, insulin resistance and type 2 diabetes mellitus are all
linked to cardiovascular diseases such as cardiac hypertrophy and heart failure. Diabetic …