L Zhuang, Z Ye, L Li, L Yang, W Gong - Vaccines, 2023 - mdpi.com
Tuberculosis (TB), caused by Mycobacterium tuberculosis (MTB), is a prevalent global infectious disease and a leading cause of mortality worldwide. Currently, the only available …
Over the past 50 years, the Mycobacterium bovis bacille Calmette–Guérin (BCG) vaccine against tuberculosis (TB) has maintained its position as the world's most widely used …
Mycobacterium tuberculosis has a penetrance of its host population that would be the envy of most human pathogens. About one-third of the human population would have a positive …
A Arbues, JI Aguilo, J Gonzalo-Asensio, D Marinova… - Vaccine, 2013 - Elsevier
The development of a new tuberculosis vaccine is an urgent need due to the failure of the current vaccine, BCG, to protect against the respiratory form of the disease. MTBVAC is an …
B Mathema, NE Kurepina, PJ Bifani… - Clinical microbiology …, 2006 - Am Soc Microbiol
Molecular epidemiologic studies of tuberculosis (TB) have focused largely on utilizing molecular techniques to address short-and long-term epidemiologic questions, such as in …
Tissue-resident memory T cells (TRM) comprise a newly defined subset, which comprises a major component of lymphocyte populations in diverse peripheral tissue sites, including …
NE Nieuwenhuizen, SHE Kaufmann - Frontiers in immunology, 2018 - frontiersin.org
Tuberculosis (TB), caused by the intracellular bacterium Mycobacterium tuberculosis (Mtb), remains a major health threat. A live, attenuated mycobacterium known as Bacille Calmette …
Abstract The Bacille Calmette–Guérin (BCG) vaccine has been used for more than 80 years to protect against tuberculosis. Worldwide, over 90% of children are immunized with BCG …
HM Vordermeier, B Villarreal-Ramos… - Infection and …, 2009 - Am Soc Microbiol
Previous work with small-animal laboratory models of tuberculosis has shown that vaccination strategies based on heterologous prime-boost protocols using Mycobacterium …