Morphological, cellular, and molecular basis of brain infection in COVID-19 patients

F Crunfli, VC Carregari, FP Veras… - Proceedings of the …, 2022 - National Acad Sciences
Although increasing evidence confirms neuropsychiatric manifestations associated mainly
with severe COVID-19 infection, long-term neuropsychiatric dysfunction (recently …

The microbiota‐gut‐brain axis and epilepsy from a multidisciplinary perspective: Clinical evidence and technological solutions for improvement of in vitro preclinical …

F Fusco, S Perottoni, C Giordano, A Riva… - Bioengineering & …, 2022 - Wiley Online Library
Epilepsy is a common neurological disease characterized by the enduring predisposition of
the brain to generate seizures. Among the recognized causes, a role played by the gut …

Modeling the Human Brain With ex vivo Slices and in vitro Organoids for Translational Neuroscience

GO Nogueira, PP Garcez, C Bardy… - Frontiers in …, 2022 - frontiersin.org
Advances in translational neuroscience require experimental models recapitulating the
complexity of the human brain. In contrast to conventional 2D cell culture models and animal …

SARS‐CoV‐2 infection impacts carbon metabolism and depends on glutamine for replication in Syrian hamster astrocytes

LG de Oliveira, Y de Souza Angelo… - Journal of …, 2022 - Wiley Online Library
COVID‐19 causes more than million deaths worldwide. Although much is understood about
the immunopathogenesis of the lung disease, a lot remains to be known on the neurological …

NMDA glutamate receptor antagonist MK‐801 induces proteome changes in adult human brain slices which are partially counteracted by haloperidol and clozapine

V de Almeida, ND Mendes, GS Zuccoli… - Journal of …, 2024 - Wiley Online Library
Deciphering the molecular pathways associated with N‐methyl‐D‐aspartate receptor
(NMDAr) hypofunction and its interaction with antipsychotics is necessary to advance our …

Neural infection by oropouche virus in adult human brain slices induces an inflammatory and toxic response

GM Almeida, JP Souza, ND Mendes… - Frontiers in …, 2021 - frontiersin.org
Oropouche virus (OROV) is an emerging arbovirus in South and Central Americas with high
spreading potential. OROV infection has been associated with neurological complications …

A freeze-and-thaw-induced fragment of the microtubule-associated protein tau in rat brain extracts: implications for the biochemical assessment of neurotoxicity

IC Vasconcelos, RM Campos… - Bioscience …, 2021 - portlandpress.com
Tau is a microtubule-associated protein (MAP) responsible for controlling the stabilization of
microtubules in neurons. Tau function is regulated by phosphorylation. However, in some …

[PDF][PDF] Supplementary Information for “Morphological, cellular and molecular basis of brain infection in COVID-19 patients”

F Crunfli, VC Carregari, FP Veras - pdfs.semanticscholar.org
Supplementary Information for “Morphological, cellular and molecular basis of brain infection in
COVID-19 patients” Page 1 1 Supplementary Information for “Morphological, cellular and …

Estudo da infecção do sistema nervoso central pelo vírus Oropouche em um modelo de fatias de cérebro humano adulto

GM Almeida - 2020 - teses.usp.br
O vírus Oropouche (OROV), da família Peribunyaviridae, gênero Orthobunyavirus, é um
agente causador da arbovirose chamada febre de Oropouche. Esse vírus possui uma …