The crucial role of cancer stem cells (CSC s) in the pathology of malignant diseases has
been extensively studied during the last decade. Nestin, a class VI intermediate filament …

Cancer is one of the major and leading causes of death worldwide. Two of the greatest
challenges in fighting cancer are early detection and effective treatments with no or …

The surface of a cell represents a collection of macromolecules, which provides the cell with
a unique cellular landscape specific to the type and state of the cell. Ligands that …

Despite the application of aggressive surgery, radiotherapy and chemotherapy in clinics,
brain tumors are still a difficult health challenge due to their fast development and poor …

Abstract Introduction We investigated Nestin expression in triple-negative breast cancer and
examined how the modulation of Nestin expression affects cell cycle progression, survival …

Cancer stem cells (CSCs) are the most aggressive cell type in many malignancies. Cell
surface proteins are generally used to isolate and characterize CSCs. Therefore, the …

Despite advances in understanding of the molecular pathogenesis of glioma, outcomes
remain dismal. Developing successful treatments for glioma requires faithful in vivo disease …

Intermediate filaments (IFs) of the nervous system, including neurofilaments, α-internexin,
glial fibrillary acidic protein, synemin, nestin, peripherin and vimentin, are finely expressed …

Glioblastoma multiforme (GBM) is the most common and aggressive primary brain tumor in
humans. It accounts for fifty-two percent of primary brain malignancies in the United States …

Highlights•Improved early cancer detection, combined with better therapeutic monitoring
procedures and dynamic treatment options, is needed to combat tumor persistence …