Nanoparticles for targeted brain drug delivery: what do we know?

RGR Pinheiro, AJ Coutinho, M Pinheiro… - International Journal of …, 2021 - mdpi.com
The blood–brain barrier (BBB) is a barrier that separates the blood from the brain tissue and
possesses unique characteristics that make the delivery of drugs to the brain a great …

Biomimetic nanotechnology toward personalized vaccines

J Zhou, AV Kroll, M Holay, RH Fang… - Advanced …, 2020 - Wiley Online Library
While traditional approaches for disease management in the era of modern medicine have
saved countless lives and enhanced patient well‐being, it is clear that there is significant …

Structure, function and evolution of three-finger toxins: mini proteins with multiple targets

RM Kini, R Doley - Toxicon, 2010 - Elsevier
Snake venoms are complex mixtures of pharmacologically active peptides and proteins.
These protein toxins belong to a small number of superfamilies of proteins. Three-finger …

Peptide ligand-mediated targeted drug delivery of nanomedicines

Z Jiang, J Guan, J Qian, C Zhan - Biomaterials science, 2019 - pubs.rsc.org
Targeted drug delivery is emerging as a promising strategy to achieve better clinical
outcomes. Actively targeted drug delivery that utilizes overexpressed receptors or antigens …

Neurotoxicity in snakebite—the limits of our knowledge

UK Ranawaka, DG Lalloo… - PLoS neglected tropical …, 2013 - journals.plos.org
Snakebite is classified by the WHO as a neglected tropical disease. Envenoming is a
significant public health problem in tropical and subtropical regions. Neurotoxicity is a key …

[图书][B] Handbook of venoms and toxins of reptiles

SP Mackessy - 2016 - taylorfrancis.com
The Handbook of Venoms and Toxins of Reptiles offers" one-stop shopping" to all biologists,
biochemists, toxicologists, physicians, clinicians, and epidemiologists, and informed …

Molecular evolution and phylogeny of elapid snake venom three-finger toxins

BG Fry, W Wüster, RM Kini, V Brusic, A Khan… - Journal of molecular …, 2003 - Springer
Animal venom components are of considerable interest to researchers across a wide variety
of disciplines, including molecular biology, biochemistry, medicine, and evolutionary …

Biomimetic strategies for targeted nanoparticle delivery

D Dehaini, RH Fang, L Zhang - Bioengineering & translational …, 2016 - Wiley Online Library
Nanoparticle‐based drug delivery and imaging platforms have become increasingly popular
over the past several decades. Among different design parameters that can affect their …

Three-finger α-neurotoxins and the nicotinic acetylcholine receptor, forty years on

S Nirthanan, MCE Gwee - Journal of pharmacological sciences, 2004 - jstage.jst.go.jp
The discovery, about forty years ago, of a-bungarotoxin, a three-finger a-neurotoxin from
Bungarus multicinctus venom, enabled the isolation of the nicotinic acetylcholine receptor …

Denmotoxin, a three-finger toxin from the colubrid snake Boiga dendrophila (Mangrove Catsnake) with bird-specific activity

J Pawlak, SP Mackessy, BG Fry, M Bhatia… - Journal of Biological …, 2006 - ASBMB
Boiga dendrophila (mangrove catsnake) is a colubrid snake that lives in Southeast Asian
lowland rainforests and mangrove swamps and that preys primarily on birds. We have …