Nearly all bacteria form biofilms as a strategy for survival and persistence. Biofilms are
associated with biotic and abiotic surfaces and are composed of aggregates of cells that are …

Biofilms are a widely observed growth mode in which microbial communities are spatially
structured and embedded in a polymeric extracellular matrix. Here, we focus on the model …

The most common prokaryotic signal transduction mechanisms are the one-component
systems in which a single polypeptide contains both a sensory domain and a DNA-binding …

Two chemical signaling systems, quorum sensing (QS) and 3′, 5′-cyclic diguanylic acid (c-
di-GMP), reciprocally control biofilm formation in Vibrio cholerae. QS is the process by which …

Biofilms are complex microbial communities consisting of microcolonies embedded in a
matrix of self-produced polymer substances. Biofilm cells show much greater resistance to …

The coordination of group behaviors in bacteria is accomplished via the cell-cell signaling
process called quorum sensing. Vibrios have historically been models for studying bacterial …

Vibrio cholerae is a human pathogen that causes the life-threatening diarrheal disease
cholera. A type VI secretion system (T6SS) was recently shown to be required for full …

Background Many bacteria, including Vibrio spp., regulate virulence gene expression in a
cell-density dependent way through a communication process termed quorum sensing (QS) …

Quorum sensing is the process of cell‐to‐cell communication by which bacteria
communicate via secreted signal molecules called autoinducers. As cell population density …

LuxR-type transcription factors are the master regulators of quorum sensing in vibrios. LuxR
proteins are unique members of the TetR superfamily of transcription factors because they …