Gene Drive and Symbiont Technologies for Control of Mosquito-Borne Diseases
GH Wang, A Hoffmann… - Annual Review of …, 2024 - annualreviews.org
Mosquito-borne diseases, such as dengue and malaria, pose a significant burden to global
health. Current control strategies with insecticides are only moderately effective. Scalable …
health. Current control strategies with insecticides are only moderately effective. Scalable …
Humidity–The overlooked variable in the thermal biology of mosquito‐borne disease
Vector‐borne diseases cause significant financial and human loss, with billions of dollars
spent on control. Arthropod vectors experience a complex suite of environmental factors that …
spent on control. Arthropod vectors experience a complex suite of environmental factors that …
A comprehensive review of Wolbachia-mediated mechanisms to control dengue virus transmission in Aedes aegypti through innate immune pathways
The Dengue virus (DENV), primarily spread by Aedes aegypti and also by Aedes albopictus
in some regions, poses significant global health risks. Alternative techniques are urgently …
in some regions, poses significant global health risks. Alternative techniques are urgently …
Low-input PacBio sequencing generates high-quality individual fly genomes and characterizes mutational processes
Long-read sequencing, exemplified by PacBio, revolutionizes genomics, overcoming
challenges like repetitive sequences. However, the high DNA requirement (> 1 µg) is …
challenges like repetitive sequences. However, the high DNA requirement (> 1 µg) is …
Susceptibility of Wolbachia mosquito control to temperature shifts
EP Caragata - Nature Climate Change, 2023 - nature.com
Susceptibility of Wolbachia mosquito control to temperature shifts | Nature Climate Change Skip
to main content Thank you for visiting nature.com. You are using a browser version with limited …
to main content Thank you for visiting nature.com. You are using a browser version with limited …
Aedes aegypti microbiome composition covaries with the density of Wolbachia infection
J Pascar, H Middleton, S Dorus - Microbiome, 2023 - Springer
Background Wolbachia is a widespread bacterial endosymbiont that can inhibit vector
competency when stably transinfected into the mosquito, Aedes aegypti, a primary vector of …
competency when stably transinfected into the mosquito, Aedes aegypti, a primary vector of …
Wolbachia wAlbB remains stable in Aedes aegypti over 15 years but exhibits genetic background-dependent variation in virus blocking
X Liang, CH Tan, Q Sun, M Zhang, PSJ Wong… - PNAS …, 2022 - academic.oup.com
The ability of the maternally transmitted endosymbiotic bacterium Wolbachia to induce
cytoplasmic incompatibility (CI) and virus blocking makes it a promising weapon for …
cytoplasmic incompatibility (CI) and virus blocking makes it a promising weapon for …
Developing Wolbachia-based disease interventions for an extreme environment
PA Ross, S Elfekih, S Collier, MJ Klein, SS Lee… - PLoS …, 2023 - journals.plos.org
Aedes aegypti mosquitoes carrying self-spreading, virus-blocking Wolbachia bacteria are
being deployed to suppress dengue transmission. However, there are challenges in …
being deployed to suppress dengue transmission. However, there are challenges in …
wMel replacement of dengue-competent mosquitoes is robust to near-term climate change
Rising temperatures are impacting the range and prevalence of mosquito-borne diseases. A
promising biocontrol technology replaces wild mosquitoes with those carrying the virus …
promising biocontrol technology replaces wild mosquitoes with those carrying the virus …
Complex effects of environment and Wolbachia infections on the life history of Drosophila melanogaster hosts
A Strunov, S Lerch, WU Blanckenhorn… - Journal of …, 2022 - academic.oup.com
Wolbachia bacteria are common endosymbionts of many arthropods found in gonads and
various somatic tissues. They manipulate host reproduction to enhance their transmission …
various somatic tissues. They manipulate host reproduction to enhance their transmission …