Hyperspectral imaging (HSI) is an emerging imaging modality for medical applications,
especially in disease diagnosis and image-guided surgery. HSI acquires a three …

Advancements in coherent Raman scattering (CRS) microscopy have enabled label-free
visualization and analysis of functional, endogenous biomolecules in living systems. When …

Raman scattering provides an intrinsic fingerprint of chemical composition. Spontaneous
Raman spectroscopy has been used for many decades to interrogate biological materials …

Stimulated Raman scattering microscopy allows label-free chemical imaging and has
enabled exciting applications in biology, material science and medicine. It provides a major …

First, the potential role of Raman-based techniques in biomedicine is introduced. Second,
an overview about the instrumentation for spontaneous and coherent Raman scattering …

Spectroscopic imaging has been an increasingly critical approach for unveiling specific
molecules in biological environments. Toward this goal, we demonstrate hyperspectral …

Hyperspectral imaging (HSI) is an emerging imaging modality for medical applications,
especially in disease diagnosis and image-guided surgery. HSI acquires three-dimensional …

A tutorial article is presented for the use of linear and nonlinear Raman microspectroscopies
in biomedical diagnostics. Coherent anti-Stokes Raman scattering (CARS) is the most …

Cholesterol crystals (ChCs) have been identified as a major factor of plaque vulnerability
and as a potential biomarker for atherosclerosis. Yet, due to the technical challenge of …

Significance: Although the clinical potential for Raman spectroscopy (RS) has been
anticipated for decades, it has only recently been used in neurosurgery. Still, few devices …