Of all microorganisms in the human body, the largest and most complex population resides
in the gastrointestinal (GI) tract. The gut microbiota continuously adapts to the host …

Small intestinal bacterial overgrowth (SIBO) is one manifestation of gut microbiome
dysbiosis and is highly prevalent in IBS (Irritable Bowel Syndrome). SIBO can be diagnosed …

The pathogenesis of irritable bowel syndrome (IBS), once thought to be largely psychogenic
in origin, is now understood to be multifactorial. One of the reasons for this paradigm shift is …

The emerging field of metabolomics, in which a large number of small-molecule metabolites
from body fluids or tissues are detected quantitatively in a single step, promises immense …

Background The symptoms and signs of small intestinal bacterial overgrowth (SIBO) are
often identical to a variety of diseases and can lead to diagnostic confusion. Aims To review …

Gut microbiota and their metabolites like bile acid (BA) have been investigated as causes of
irritable bowel syndrome (IBS) symptoms. Primary BAs are synthesized and conjugated in …

Insulin is as a major postprandial hormone with profound effects on carbohydrate, fat, and
protein metabolism. In the absence of exogenous insulin, patients with type 1 diabetes …

In the clinical setting, small intestinal bacterial overgrowth (SIBO) is a frequent, but under-
diagnosed entity. SIBO is linked to various gastrointestinal (GI) and non-GI disorders with …

Obesity and diabetes arise from an intricate interplay between both genetic and
environmental factors. It is well recognized that obesity plays an important role in the …

Nuclear magnetic resonance (NMR) spectroscopy is a major analytical method used in the
growing field of metabolomics. Although NMR is relatively less sensitive than mass …