BERT4Bitter: a bidirectional encoder representations from transformers (BERT)-based model for improving the prediction of bitter peptides

P Charoenkwan, C Nantasenamat, MM Hasan… - …, 2021 - academic.oup.com
Motivation The identification of bitter peptides through experimental approaches is an
expensive and time-consuming endeavor. Due to the huge number of newly available …

StackIL6: a stacking ensemble model for improving the prediction of IL-6 inducing peptides

P Charoenkwan, W Chiangjong… - Briefings in …, 2021 - academic.oup.com
The release of interleukin (IL)-6 is stimulated by antigenic peptides from pathogens as well
as by immune cells for activating aggressive inflammation. IL-6 inducing peptides are …

Deepm5C: a deep-learning-based hybrid framework for identifying human RNA N5-methylcytosine sites using a stacking strategy

MM Hasan, S Tsukiyama, JY Cho, H Kurata, MA Alam… - Molecular Therapy, 2022 - cell.com
As one of the most prevalent post-transcriptional epigenetic modifications, N5-
methylcytosine (m5C) plays an essential role in various cellular processes and disease …

Computational prediction and interpretation of cell-specific replication origin sites from multiple eukaryotes by exploiting stacking framework

L Wei, W He, A Malik, R Su, L Cui… - Briefings in …, 2021 - academic.oup.com
Origins of replication sites (ORIs), which refers to the initiative locations of genomic DNA
replication, play essential roles in DNA replication process. Detection of ORIs' distribution in …

MLCPP 2.0: an updated cell-penetrating peptides and their uptake efficiency predictor

B Manavalan, MC Patra - Journal of Molecular Biology, 2022 - Elsevier
Cell-penetrating peptides (CPPs) translocate into the cell as various biologically active
conjugates and possess numerous biomedical applications. Several machine learning …

STALLION: a stacking-based ensemble learning framework for prokaryotic lysine acetylation site prediction

S Basith, G Lee, B Manavalan - Briefings in Bioinformatics, 2022 - academic.oup.com
Protein post-translational modification (PTM) is an important regulatory mechanism that
plays a key role in both normal and disease states. Acetylation on lysine residues is one of …

SAPPHIRE: A stacking-based ensemble learning framework for accurate prediction of thermophilic proteins

P Charoenkwan, N Schaduangrat, MA Moni… - Computers in Biology …, 2022 - Elsevier
Thermophilic proteins (TPPs) are important in the field of protein biochemistry and
development of new enzymes. Thus, computational methods must be urgently developed to …

Comparative analysis of machine learning-based approaches for identifying therapeutic peptides targeting SARS-CoV-2

B Manavalan, S Basith, G Lee - Briefings in bioinformatics, 2022 - academic.oup.com
Abstract Coronavirus disease 2019 (COVID-19) has impacted public health as well as
societal and economic well-being. In the last two decades, various prediction algorithms and …

THRONE: a new approach for accurate prediction of human RNA N7-methylguanosine sites

W Shoombuatong, S Basith, T Pitti, G Lee… - Journal of Molecular …, 2022 - Elsevier
Abstract N 7-methylguanosine (m7G) is an essential, ubiquitous, and positively charged
modification at the 5′ cap of eukaryotic mRNA, modulating its export, translation, and …

UMPred-FRL: A new approach for accurate prediction of umami peptides using feature representation learning

P Charoenkwan, C Nantasenamat, MM Hasan… - International journal of …, 2021 - mdpi.com
Umami ingredients have been identified as important factors in food seasoning and
production. Traditional experimental methods for characterizing peptides exhibiting umami …