Diseases of muscle that are caused by pathological interactions between muscle and the
immune system are devastating, but rare. However, muscle injuries that involve trauma and …

Growth differentiation factor 11 (GDF11) and myostatin (or GDF8) are closely related
members of the transforming growth factor β superfamily and are often perceived to serve …

Background Injection of exogenous mitochondria has been shown to improve the ischaemia‐
damaged myocardium, but the effect of mitochondrial transplant therapy (MTT) to restore …

Adult skeletal muscle possesses extraordinary regeneration capacities. After muscle injury
or exercise, large numbers of newly formed muscle fibers are generated within a week as a …

The cellular turnover required for skeletal muscle maintenance and repair is mediated by
resident stem cells, also termed satellite cells. Satellite cells normally reside in a quiescent …

Muscle regeneration recapitulates many aspects of embryonic myogenesis and is an
important homeostatic process of the adult skeletal muscle, which, after development …

Lizards, which are amniote vertebrates like humans, are able to lose and regenerate a
functional tail. Understanding the molecular basis of this process would advance …

Muscle wasting disease indications are among the most debilitating and often deadly
noncommunicable disease states. As a comorbidity, muscle wasting is associated with …

Muscular dystrophy is a heterogenous group of hereditary muscle disorders caused by
mutations in the genes responsible for muscle development, and is generally defined by a …

Nfix belongs to a family of four highly conserved proteins that act as transcriptional activators
and/or repressors of cellular and viral genes. We previously showed a pivotal role for Nfix in …