Multiple endocrine neoplasia type 1: latest insights

ML Brandi, SK Agarwal, ND Perrier, KE Lines… - Endocrine …, 2021 - academic.oup.com
Multiple endocrine neoplasia type 1 (MEN1), a rare tumor syndrome that is inherited in an
autosomal dominant pattern, is continuing to raise great interest for endocrinology …

Androgen receptor signaling in castration-resistant prostate cancer: a lesson in persistence

I Coutinho, TK Day, WD Tilley… - Endocrine-related …, 2016 - erc.bioscientifica.com
The androgen receptor (AR) signaling axis drives all stages of prostate cancer, including the
lethal, drug-resistant form of the disease termed castration-resistant prostate cancer (CRPC) …

Causes of death and prognostic factors in multiple endocrine neoplasia type 1: a prospective study: comparison of 106 MEN1/Zollinger-Ellison syndrome patients with …

T Ito, H Igarashi, H Uehara, MJ Berna, RT Jensen - Medicine, 2013 - journals.lww.com
Multiple endocrine neoplasia type 1 (MEN1) is classically characterized by the development
of functional or nonfunctional hyperplasia or tumors in endocrine tissues (parathyroid …

MEN1 redefined, a clinical comparison of mutation-positive and mutation-negative patients

JM De Laat, RB van der Luijt, CRC Pieterman… - BMC medicine, 2016 - Springer
Abstract Background Multiple Endocrine Neoplasia type 1 (MEN1) is diagnosed when two
out of the three primary MEN1-associated endocrine tumors occur in a patient. Up to 10 …

[HTML][HTML] Hypercalcitoninemia is not pathognomonic of medullary thyroid carcinoma

S Toledo, DM Lourenço Jr, MA Santos, MR Tavares… - Clinics, 2009 - SciELO Brasil
Hypercalcitoninemia has frequently been reported as a marker for medullary thyroid
carcinoma. Currently, calcitonin measurements are mostly useful in the evaluation of tumor …

Challenges and controversies in management of pancreatic neuroendocrine tumours in patients with MEN1

CJ Yates, PJ Newey, RV Thakker - The Lancet Diabetes & …, 2015 - thelancet.com
Multiple endocrine neoplasia type 1 (MEN1), an autosomal dominant disorder, is
characterised by the occurrence of pancreatic neuroendocrine tumours (P-NETs) in …

[HTML][HTML] Genetics of multiple endocrine neoplasia type 1 syndrome: what's new and what's old

A Falchetti - F1000Research, 2017 - ncbi.nlm.nih.gov
Despite its identification in 1997, the functions of the MEN1 gene—the main gene underlying
multiple endocrine neoplasia type 1 syndrome—are not yet fully understood. In addition …

Natural course and survival of neuroendocrine tumors of thymus and lung in MEN1 patients

JM De Laat, CR Pieterman… - The Journal of …, 2014 - academic.oup.com
Context: The natural course and survival of neuroendocrine tumors (NETs) of thymus (Th)
and lung in multiple endocrine neoplasia type 1 (MEN1) patients are still unknown …

Thoracic and duodenopancreatic neuroendocrine tumors in multiple endocrine neoplasia type 1: natural history and function of menin in tumorigenesis

CRC Pieterman, EB Conemans… - Endocrine-related …, 2014 - erc.bioscientifica.com
Mutations of the multiple endocrine neoplasia type 1 (MEN1) gene lead to loss of function of
its protein product menin. In keeping with its tumor suppressor function in endocrine tissues …

[HTML][HTML] Multiple endocrine neoplasia type 1 (MEN1): not only inherited endocrine tumors

A Falchetti, F Marini, E Luzi, F Giusti, L Cavalli… - Genetics in …, 2009 - Elsevier
MEN 1 is a rare hereditary cancer syndrome which manifests a variety of endocrine and non-
endocrine neoplasms and lesions. Growing knowledge of this condition in both its molecular …