Mind the translational gap: using iPS cell models to bridge from genetic discoveries to perturbed pathways and therapeutic targets

G Pintacuda, JM Martín, KC Eggan - Molecular Autism, 2021 - Springer
Autism spectrum disorder (ASD) comprises a group of neurodevelopmental disorders
characterized by impaired social interactions as well as the presentation of restrictive and …

Advancements of 3D bioprinting in regenerative medicine: Exploring cell sources for organ fabrication

Y Ma, B Deng, R He, P Huang - Heliyon, 2024 - cell.com
Abstract 3D bioprinting has unlocked new possibilities for generating complex and
functional tissues and organs. However, one of the greatest challenges lies in selecting the …

Cell transdifferentiation and reprogramming in disease modeling: insights into the neuronal and cardiac disease models and current translational strategies

RS Kalra, JK Dhanjal, M Das, B Singh, R Naithani - Cells, 2021 - mdpi.com
Cell transdifferentiation and reprogramming approaches in recent times have enabled the
manipulation of cell fate by enrolling exogenous/artificial controls. The chemical/small …

Epigenetic control of reprogramming and transdifferentiation by histone modifications

H Qin, A Zhao, C Zhang, X Fu - Stem Cell Reviews and Reports, 2016 - Springer
Somatic cells can be reprogrammed to pluripotent stem cells or transdifferentiate to another
lineage cell type. Much efforts have been made to unravel the epigenetic mechanisms …

[PDF][PDF] 抗菌药物合理使用对临床手术感染率影响的比较医学分析

黄小燕, 赵喜荣, 曹瑞丽 - 中国比较医学杂志, 2018 - zgbjyx.cnjournals.com
目的了解我院清洁切口感染与抗菌药物合理使用的相关性, 比较分析抗菌药物合理使用对临床
手术感染率影响, 为规范围手术期合理用药和临床干预提供科学依据. 方法通过查阅出院病历 …

Cardiac stem cells: a plethora of potential therapies for myocardial regeneration within reach

E Gallego-Colon, E Oliver - Stem Cell Genetics for Biomedical Research …, 2018 - Springer
The limited regenerative capacity of the adult heart hinders cardiac regeneration and still
remains an unsolved therapeutic target. In the last decade, the development of cell-based …

Transdiferencijacija alfa ćelija pankreasa miša u ćelije koje proizvode insulin ciljanom metilacijom DNK primenom Epi-CRISPR sistema

MB Đorđević - Универзитет у Београду, 2023 - nardus.mpn.gov.rs
Ekspresija gena za Arx (engl. Aristaless related homeobox) koji ima glavnu ulogu u
održavanju identiteta alfa ćelija endokrinog pankreasa regulisana je metilacijom i …

THE PARKINSON'S DISEASE ASSOCIATED PINK1-PARKIN PATHWAY IN PATHOLOGY AND DEVELOPMENT

J Jarazo - 2018 - orbilu.uni.lu
Parkinson's disease (PD) has an aetiology not completely understood. One of the
hypothesis in the field is that many neurodegenerative diseases are influenced by …