Vitamin D deficiency is the main cause of nutritional rickets in children and osteomalacia in
adults. There is consensus that nutritional access to vitamin D can be estimated by …

The essential metal manganese (Mn) induces incurable neurotoxicity at elevated levels that
manifests as parkinsonism in adults and fine motor and executive function deficits in …

Abstract Arginase, a manganese (Mn)-dependent enzyme, is indispensable for urea
generation and ammonia disposal in the liver. The potential role of fructose in Mn and …

Antimicrobial peptides (AMPs) are important mediators of intestinal immune surveillance.
However, the regional heterogeneity of AMPs and its regulatory mechanisms remain …

Manganese (Mn) is an essential metal that induces incurable parkinsonism at elevated
levels. However, unlike other essential metals, mechanisms that regulate mammalian Mn …

Colorectal cancer (CRC) is one of the most life‐threatening neoplasias in terms of incidence
and mortality worldwide. Vitamin D deficiency has been associated with an increased risk of …

Human intestinal epithelial organoids (enteroids and colonoids) are tissue cultures used for
understanding the physiology of the human intestinal epithelium. Here, we explored the …

Vitamin D regulates a plethora of physiological processes in the human body and has been
proposed to exert several anticancer effects. Epigenetics plays an important role in …

1, 25-dihydroxyvitamin D (VD) regulates intestinal calcium absorption in the small intestine
(SI) and also reduces risk of colonic inflammation and cancer. However, the intestine …

Introduction Neuropilin 2 (NRP2) mediates the effects of class 3 semaphorins and vascular
endothelial growth factor and is implicated in axonal guidance and angiogenesis. Moreover …