Background Lupus nephritis (LN) is a severe consequence of systemic lupus erythematosus
(SLE) that affects approximately 40% of patients. Pathogenic immune complexes that are …

Lupus nephritis (LN) is the most common serious complication of systemic lupus
erythematosus (SLE). The pathogenesis of LN is complex, and the majority causes of LN are …

Objective: Recent studies on double negative B cells (DN B cells) suggested that they have
potential pathogenic roles in systemic lupus erythematosus (SLE). This study aimed to …

Brain pericytes regulate cerebral blood flow, maintain the integrity of the blood-brain barrier
(BBB), and facilitate the removal of amyloid β (Aβ), which is critical to healthy brain activity …

Systemic lupus erythematosus (SLE) primarily affects women of childbearing age. One of the
major changes in SLE focuses on the timing of a successful pregnancy. In the past …

The outcome of lupus nephritis (LN) has changed since the introduction of glucocorticoids
(GCs), which dramatically reduced the mortality related to one of the most severe …

Until the etiopathogenic factor (s) of autoimmune and autoinflammatory rheumatic disorders
will be identified, their classification into entities will continue. However, their similar clinical …

Objectives Low copy numbers and deletion of complement C4 genes are potent risk factors
for systemic lupus erythematosus (SLE). However, it is not known whether this genetic …

B cells are recognized as key participants in various autoimmune diseases, including
systemic lupus erythematosus (SLE). Although sets of transcription factors and cytokines are …

We present the cases of three patients with severe, life-threatening coronavirus disease
2019 (COVID-19) who had failed to achieve substantial improvement on intial treatment …