A meta-analysis comparing the efficacy of four 5-HT3-receptor antagonists for acute chemotherapy-induced emesis

K Jordan, A Hinke, A Grothey, W Voigt, D Arnold… - Supportive Care in …, 2007 - Springer
Goals of work Comparing antiemetic efficacy of different 5-HT 3-receptor antagonists (5-HT 3
RAs) is difficult due to inter-study variability. Therefore, a meta-analysis was performed to …

Antiemetics for adults for prevention of nausea and vomiting caused by moderately or highly emetogenic chemotherapy: a network meta‐analysis

V Piechotta, A Adams, M Haque… - Cochrane Database …, 2021 - cochranelibrary.com
Background About 70% to 80% of adults with cancer experience chemotherapy‐induced
nausea and vomiting (CINV). CINV remains one of the most distressing symptoms …

5-HT3-Receptor Antagonists for the Treatment of Nausea and Vomiting: A Reappraisal of Their Side-Effect Profile

S Goodin, R Cunningham - The oncologist, 2002 - academic.oup.com
Abstract Learning Objectives After completing this course, the reader will be able to: List the
differences in side-effect profiles of the 5-HT3-receptor antagonists. Explain the potential …

Cisplatin: an old drug with a newfound efficacy–from mechanisms of action to cytotoxicity

A Macciò, C Madeddu - Expert opinion on pharmacotherapy, 2013 - Taylor & Francis
Introduction: Cisplatin is a highly effective antineoplastic drug with an extremely current
mechanism of action. Cisplatin-induced side effects are dose-dependent and limit the …

Baseline patient characteristics, incidence of CINV, and physician perception of CINV incidence following moderately and highly emetogenic chemotherapy in Asia …

RK Hsieh, A Chan, HK Kim, S Yu, JG Kim… - Supportive Care in …, 2015 - Springer
Purpose This paper describes the incidence of chemotherapy-induced nausea and vomiting
(CINV) after highly or moderately emetogenic chemotherapy (HEC or MEC) for cancer in six …

Serotonin receptor antagonists for highly emetogenic chemotherapy in adults

A Billio, E Morello, MJ Clarke - Cochrane Database of …, 2010 - cochranelibrary.com
Background Serotonin receptor antagonists (5‐HT 3 RAs) are used to control chemotherapy‐
induced emesis. Although they have the same general mechanism of action (blockade of …

Simultaneous determination of dexamethasone, ondansetron, granisetron, tropisetron, and azasetron in infusion samples by HPLC with DAD detection

F Chen, L Wang, J Guo, X Shi… - Journal of Analytical …, 2017 - Wiley Online Library
A simple and rapid high‐performance liquid chromatography with diode array detector
(HPLC‐DAD) method has been developed and validated for simultaneous quantification of …

Efficacy, safety and effectiveness of ondansetron compared to other serotonin-3 receptor antagonists (5-HT3RAs) used to control chemotherapy-induced nausea and …

GPR Simino, LP Marra, EIG Andrade… - Expert Review of …, 2016 - Taylor & Francis
Introduction: Chemotherapy-induced nausea and vomiting are adverse effects responsible
for worsening quality of life in cancer patients. To assess the efficacy, safety and …

5-HT3 Receptor Antagonists for Prevention of Late Acute-Onset Emesis

M Constenla - Annals of Pharmacotherapy, 2004 - journals.sagepub.com
OBJECTIVE To review the currently available literature on the efficacy of the 5–HT3 receptor
antagonists in the prevention of late acute-onset chemotherapy-induced nausea and …

Optimising antiemetic therapy: what are the problems and how can they be overcome?

M Aapro - Current medical research and opinion, 2005 - Taylor & Francis
Background: Management of chemotherapy-or radiotherapy-induced emesis has improved
significantly following the introduction of the 5‐HT3-receptor antagonists. Prophylactic use of …