Microtubules are essential dynamic polymers composed of α/β-tubulin heterodimers. They
support intracellular trafficking, cell division, cellular motility, and other essential cellular …

Apicomplexa are obligatory intracellular parasites that sense and actively invade host cells.
Invasion is a conserved process that relies on the timely and spatially controlled exocytosis …

Sperm motility is crucial to reproductive success in sexually reproducing organisms.
Impaired sperm movement causes male infertility, which is increasing globally. Sperm are …

Sperm motility is crucial for successful fertilization. Highly decorated doublet microtubules
(DMTs) form the sperm tail skeleton, which propels the movement of spermatozoa. Using …

Microtubules are a ubiquitous eukaryotic cytoskeletal element typically consisting of 13
protofilaments arranged in a hollow cylinder. This arrangement is considered the canonical …

The protein tau associates with microtubules to maintain neuronal health. Posttranslational
modifications of tau interfere with this binding, leading to tau aggregation in …

The cilium-centrosome complex contains triplet, doublet, and singlet microtubules. The
lumenal surfaces of each microtubule within this diverse array are decorated by microtubule …

A pair of extensively modified microtubules form the central apparatus (CA) of the axoneme
of most motile cilia, where they regulate ciliary motility. The external surfaces of both CA …

Apicomplexan parasites are a group of eukaryotic protozoans with diverse biology that have
affected human health like no other group of parasites. These obligate intracellular parasites …

The recent revolution in cryo-electron microscopy (cryo-EM) has made it possible to
determine macromolecular structures directly from cell extracts. However, identifying the …