Arrhythmogenic remodeling in the failing heart

Z Husti, A Varró, I Baczkó - Cells, 2021 - mdpi.com
Chronic heart failure is a clinical syndrome with multiple etiologies, associated with
significant morbidity and mortality. Cardiac arrhythmias, including ventricular …

Recent insights into mechanisms and clinical approaches to electrical storm

I Elsokkari, Y Tsuji, JL Sapp, S Nattel - Canadian Journal of Cardiology, 2022 - Elsevier
Electrical storm, characterized by repetitive ventricular tachycardia/ventricular fibrillation
over a short period, is becoming more common with widespread use of implantable …

Regulation of sinus node pacemaking and atrioventricular node conduction by HCN channels in health and disease

MR Boyett, J Yanni, J Tellez, A Bucchi… - Progress in biophysics …, 2021 - Elsevier
The funny current, I f, was first recorded in the heart 40 or more years ago by Dario
DiFrancesco and others. Since then, we have learnt that I f plays an important role in …

Participation of ventricular trabeculae in neonatal cardiac regeneration leads to ectopic recruitment of Purkinje-like cells

L Boulgakoff, R Sturny, V Olejnickova… - Nature Cardiovascular …, 2024 - nature.com
Unlike adult mammals, newborn mice can regenerate a functional heart after myocardial
infarction; however, the precise origin of the newly formed cardiomyocytes and whether the …

Emergency management of electrical storm: A practical overview

F Guarracini, E Bonvicini, S Zanon, M Martin… - Medicina, 2023 - mdpi.com
Electrical storm is a medical emergency characterized by ventricular arrythmia recurrence
that can lead to hemodynamic instability. The incidence of this clinical condition is rising …

[HTML][HTML] A 21st century view of the anatomy of the cardiac conduction system

A Arshad, AJ Atkinson - Translational Research in Anatomy, 2022 - Elsevier
Introduction Since the discovery of the major components of the cardiac conduction system
(CCS) by the early 20th century we have seen many technological advancements that have …

Highlighting the novel effects of high-intensity interval training on some histopathological and molecular indices in the heart of type 2 diabetic rats

M Rami, S Rahdar, A Ahmadi Hekmatikar… - Frontiers in …, 2023 - frontiersin.org
Background Type 2 diabetes is one of the most common metabolic diseases in recent years
and has become an important risk factor for cardiovascular disorders. The first goal is to …

Remodelling and dysfunction of the sinus node in pulmonary arterial hypertension

SJRJ Logantha, TT Yamanushi… - … of the Royal …, 2023 - royalsocietypublishing.org
Patients with pulmonary arterial hypertension (PAH) have a high burden of arrhythmias,
including arrhythmias arising from sinus node dysfunction, and the aim of this study was to …

[HTML][HTML] Novel micro-computed tomography contrast agents to visualise the human cardiac conduction system and surrounding structures in hearts from normal, aged …

AJ Aminu, W Chen, Z Yin, M Kuniewicz… - … Research in Anatomy, 2022 - Elsevier
Research purpose The cardiac conduction system (CCS) regulates electrical impulses
across the heart and cardiac arrhythmias cause structural remodelling of the CCS. Since its …

Cardiac conduction system regeneration prevents arrhythmias after myocardial infarction

JR Sayers, H Martinez-Navarro, X Sun… - Nature Cardiovascular …, 2025 - nature.com
Arrhythmias are a hallmark of myocardial infarction (MI) and increase patient mortality. How
insult to the cardiac conduction system causes arrhythmias following MI is poorly …