Highlights•Bigels are systems that usually result from mixing a hydrogel and an
organogel.•A hydrophilic biopolymer is commonly the structuring agent of the aqueous …

Bigels have been mainly applied in the pharmaceutical sector for the controlled release of
drugs or therapeutics. However, these systems, with their intricate structures, hold great …

Hydrogels, as 3D networks containing huge amount of water, display similarity to soft
tissues, and thus they are of wide interest in tissue engineering. Hydrogels, due to …

In this paper, gelatin hydrogels and glycerol monostearate (GMS)-enhanced ethyl cellulose
(EC) oleogels were used as two phases for preparing bigels. The proportion of components …

The aim of this study was to develop and characterize the mechanical, microstructural, and
thermal behavior of a novel edible biphasic gel system also termed bigel. A combination of a …

The development of biocompatible delivery systems is a necessity for medical and topical
applications. Herein, the development of a new bigel for topical application is described. It is …

Electrospinning is an innovative technique that allows production of nanofibers and
microfibers by applying a high voltage to polymer solutions of melts. The properties of these …

Bacterial vaginosis (BV) is an infection of the vagina associated with thriving anaerobes,
such as Gardnerella vaginitis and other associated pathogens. These pathogens form a …

Mucosal tissues are often a desirable site of drug action to treat disease and engage the
immune system. However, systemically administered drugs suffer from limited bioavailability …

The formulation of biphasic gels as potential semi-solid carriers for hydrophilic and lipophilic
active substances is promising for the development of pharmaceutical preparations. The aim …