Psychological stress elicits increases in sympathetic activity accompanied by a marked
cardiovascular response. Revealing the relevant central mechanisms involved in this …

Psychoactive drugs of fungal origin, psilocin, ibotenic acid, and muscimol among them have
been proposed for recreational use and popularized since the 1960s, XX century. Despite …

Activation of neurons in the dorsomedial hypothalamus (DMH) evokes increases in mean
arterial pressure (MAP), sympathetic activity, heart rate (HR) and respiratory activity. Results …

Stimulation of neurons in the lateral/dorsolateral periaqueductal grey (l/dlPAG) produces
increases in heart rate (HR) and mean arterial pressure (MAP) that are, according to …

Peptide molecules can improve the treatment of a number of pathological conditions, but
due to their physicochemical properties, their delivery is very challenging. The study aim …

Multiple lines of evidence document a role for glutamatergic input to the hypothalamic
paraventricular nucleus (PVH) in stress‐induced activation of the hypothalamic‐pituitary …

While intense or highly arousing stressors have long been known to suppress pain,
relatively mild or chronic stress can enhance pain. The mechanisms underlying stress …

Emotional stress is now considered a risk factor for several diseases including cardiac
arrhythmias and hypertension. It is well known that the activation of neuroendocrine and …

We hypothesized that dorsomedial hypothalamus (DMH) modulates autonomic and
neuroendocrine responses in rats at rest and when subjected to restraint stress (RS). Male …

Freezing, a characteristic pattern of defensive behavior elicited by fear, is associated with a
decrease in the heart rate. Central mechanisms underlying fear bradycardia are poorly …